What's this test for?

This test is ideal if you're experiencing breathing problems, coughing, skin irritation, or asthma-like symptoms after working with spray paints, varnishes, foam insulation, or other industrial coatings. Hexamethylene diisocyanate (HDI) is a chemical commonly used in these products, and some people develop sensitivities to it over time with repeated exposure. This test checks whether your immune system has developed a specific antibody response to HDI that could explain your symptoms.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what a positive or negative result means. If your result is positive, practical next steps include reducing or eliminating direct exposure to HDI-containing products, using proper protective equipment like respirators and gloves, and improving ventilation in work areas. You can download a standard lab report from your account at any time, and if you get tested again in the future you'll be able to track changes over time using the trends feature.

Who should consider this test?

Anyone who regularly works with spray paints, polyurethane foams, adhesives, or automotive coatings and has started noticing respiratory symptoms, skin rashes, or eye irritation on the job should consider this test. It's especially relevant for people in manufacturing, auto body repair, construction, and insulation industries. If your symptoms tend to worsen during work shifts and improve on days off, that pattern is a good reason to get checked.

What symptoms indicate I may need this test?

Common signs include wheezing, shortness of breath, chest tightness, a persistent cough, or asthma attacks that seem to start or worsen at work. Some people also notice skin redness, itching, or hives after contact with isocyanate-based products. Eye irritation and a runny or stuffy nose during or after exposure can also be a clue that your body is reacting to HDI.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification once they're available, and you can log into your account anytime to view them. The report will clearly show whether the test came back positive or negative along with what that means.

How can I naturally support my respiratory health if sensitized?

If you're sensitized to HDI, the most effective step is reducing your exposure as much as possible, since no supplement or remedy replaces avoidance. Using a properly fitted respirator, working in well-ventilated spaces, and washing skin promptly after contact can all help lower your exposure. Staying well hydrated and avoiding other lung irritants like smoke or dust can also support your breathing overall.

What does a positive result mean?

A positive result means your immune system has produced specific IgE antibodies against HDI, which means you're sensitized to this chemical. This doesn't automatically mean you have a full-blown allergy — it means your body has reacted to the substance and you may be more likely to develop symptoms with continued exposure. Combining this result with your actual symptoms during exposure gives the clearest picture of what's going on.

What causes sensitization to isocyanates like HDI?

Sensitization usually develops after repeated skin contact or inhalation of isocyanate vapors or dust, often in occupational settings like spray painting, foam manufacturing, or auto body work. The more frequent and intense the exposure, the higher the chance your immune system starts reacting to it. Poor ventilation and inadequate protective equipment are common contributing factors.

How often should I retest?

If you continue working around isocyanates and your symptoms change or worsen, retesting once a year or whenever you switch jobs or exposure levels is a reasonable approach. If your symptoms resolve after reducing exposure, you may not need frequent retesting unless symptoms return. Tracking your results over time can help you see whether your sensitization is increasing or staying stable.

What should I do if my results are positive?

Start by minimizing your contact with HDI-containing products as much as possible, and make sure you're using appropriate protective gear like gloves, masks, and eye protection at work. If your breathing symptoms are severe, sudden, or getting worse quickly, seek medical care right away. Otherwise, focus on tracking your symptoms and retesting periodically to monitor changes.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Isocyanate HDI IgE Test - Occupational Allergy Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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