What's this test for?

This test is ideal if you or someone in your care has been diagnosed with acute myeloid leukemia (AML) or a brain tumor called glioma and needs more information about the specific genetic changes driving the disease. It looks for mutations in the IDH1 and IDH2 genes, which can affect how the disease behaves and which treatments may work best. This test is typically used as part of cancer workup rather than for general screening.

What's included in this test?

This test analyzes DNA from your blood or bone marrow sample to look for specific mutations in the IDH1 and IDH2 genes. These genes control an enzyme involved in cell metabolism, and mutations in them are linked to how certain cancers grow and respond to treatment, so identifying them helps guide more personalized care decisions.

What happens after I get my results?

Your results will appear in your secure online account, with an explanation of what a positive or negative mutation finding means. Because this is a specialized cancer-related test, next steps usually involve discussing treatment options with your cancer treatment team if a mutation is found, since IDH-targeted therapies are available for AML. You can download a standard lab report from your account at any time, and if repeat testing is needed to monitor treatment response, you can track those results over time using the trends feature.

When will I get my results?

Results are typically ready within about 7 days of your sample being received at the lab. This timeframe allows for the detailed genetic analysis needed to detect these specific mutations accurately. You'll receive a notification as soon as your results are available in your online account.

Who should consider this test?

This test is generally considered for people who have already been diagnosed with acute myeloid leukemia (AML) or glioma and need additional genetic information to guide treatment planning. It may also be relevant for those being evaluated for eligibility for IDH-inhibitor therapies. This is not a general wellness or screening test for the public.

What symptoms indicate I may need this test?

Symptoms alone don't usually point to needing this specific test — it's typically ordered after a cancer diagnosis is already suspected or confirmed through other means, such as abnormal blood counts, fatigue, unexplained bruising, or neurological symptoms like headaches and seizures in the case of possible glioma. If you're experiencing these symptoms without a diagnosis yet, broader blood work or imaging is usually the first step.

What is an IDH mutation and why does it matter?

IDH1 and IDH2 are genes that normally help cells process energy. When they mutate, they can produce an abnormal substance that pushes cells toward uncontrolled growth, which is why these mutations show up in certain leukemias and brain tumors. Knowing whether you have this mutation matters because it can affect your prognosis and open the door to targeted treatments designed specifically for IDH-mutated cancers.

What does a positive IDH mutation result mean?

A positive result means the test found a mutation in your IDH1 or IDH2 gene, which is present in a meaningful percentage of AML and glioma cases. This finding can influence treatment choices, since specific IDH-inhibitor medications have been approved for AML with this mutation. It's also used to help estimate how the disease may behave over time.

How often should I retest?

Retesting frequency depends on your treatment plan and disease monitoring needs rather than a fixed schedule. Many people are retested after starting treatment to see how the cancer is responding, or if there are signs the disease has changed. Your cancer treatment team can advise on the best timing based on your specific situation.

What should I do if my results are abnormal?

If a mutation is detected, the most useful next step is discussing the finding with your cancer treatment team, since it may open up options like IDH-targeted therapies. In the meantime, focus on staying consistent with any current treatment plan, keeping track of new symptoms, and maintaining good overall health through rest, nutrition, and stress management. Severe symptoms like uncontrolled bleeding, high fever, or sudden neurological changes need immediate emergency care.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

IDH1/IDH2 Mutation Test - AML & Glioma Genetic Analysis

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]