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IgG4 subclass blood test for evaluating immune conditions and IgG4-related disease

Immunoglobulin G4 (IgG4) Blood Test

Immunoglobulin G Subclass 4

  • Check immune system inflammation levels
  • Screen for unexplained gland swelling
  • Monitor antibody activity over time
$478
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained swelling in your glands, unusual fatigue, or recurring inflammation that hasn't been explained by other testing. It's also useful if you've had signs pointing to an immune system issue, such as swollen organs or unexplained allergic-type symptoms. Checking this specific antibody level can help figure out if your immune system is behaving in a way that needs closer attention.

What's included in this test?

This test measures one specific antibody subclass that plays a role in certain immune and inflammatory conditions. It matters because unusually high levels of this antibody type have been linked to a group of conditions that cause swelling and inflammation in different organs, so tracking it can help identify what's going on in your body.

What happens after I get my results?

Your results will show up in your online account with the normal range clearly explained next to your value, so you can see exactly where you stand. If your level falls outside the typical range, simple next steps might include retesting in a few months to check for changes, or making note of any symptoms to track alongside your levels. You can download a standard lab report straight from your account any time, and the trends feature lets you watch how this marker changes over time if you test again later.

How can I naturally support a balanced immune system?
Getting consistent sleep, staying hydrated, and eating a diet rich in fruits, vegetables, and omega-3 fats can help support healthy immune function. Regular moderate exercise and managing stress through activities like walking or meditation also play a role in keeping inflammation in check. Avoiding smoking and limiting alcohol can further support your body's natural immune balance.
When will I get my results?
Results are typically ready within about 7 days after your sample is collected at the lab. Once processed, they'll be uploaded directly to your secure online account, and you'll get a notification so you can log in and view them right away.
Who should consider this test?
Anyone dealing with unexplained gland swelling, persistent inflammation, or symptoms suggestive of an immune-related condition might want to consider this test. It can also be useful if you've had other test results that were unclear and you want more specific information about your immune activity. People with a family history of autoimmune or inflammatory conditions may also find this test helpful for early insight.
What symptoms indicate I may need this test?
Symptoms like swollen glands or organs, unexplained weight loss, persistent fatigue, or recurring inflammation in areas like the pancreas, salivary glands, or lymph nodes can be signs worth checking out. Some people also notice skin changes or digestive issues tied to inflammation. If these symptoms have been going on for a while without a clear explanation, this test can offer useful information.
What does a high result mean?
A higher than normal level of this antibody can be linked to certain inflammatory conditions that affect organs like the pancreas, salivary glands, or bile ducts. It doesn't automatically mean something is seriously wrong, but it's a signal worth paying attention to and possibly retesting or monitoring alongside your symptoms. Simple steps like reducing inflammatory foods, managing stress, and tracking any new symptoms can help while you figure out next steps.
How often should I retest?
If your first result is within the normal range and you have no symptoms, you likely won't need frequent retesting. If your level is elevated or you're being monitored for a specific concern, retesting every 3 to 6 months can help you track whether the number is changing over time. Your trends dashboard makes it easy to compare results side by side.
What should I do if my results are abnormal?
Start by reviewing the explanation provided with your results to understand what the number means in context. Consider tracking any symptoms you're having and retesting after a few months to see if the level changes. If you notice severe symptoms like significant swelling, pain, or rapid weight loss, it's a good idea to seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Immunoglobulin G Subclass 4 (IgG4) 185 mg/dL
Demo results
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185 mg/dL

What this means

This result is above the typical range for IgG4 antibody levels. Elevated IgG4 can sometimes be linked to inflammatory conditions affecting organs like the pancreas or salivary glands, though it isn't a diagnosis on its own. Tracking this value alongside any symptoms you have gives useful context.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Immunoglobulin G4 (IgG4) Blood Test

  • Check immune system inflammation levels
  • Screen for unexplained gland swelling
  • Monitor antibody activity over time
$478
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.