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Immunofixation and immunoglobulins test for monitoring M proteins and immune disorders

Immunofixation & Immunoglobulins Panel Blood Test

Immunofixation (IFE) and Immunoglobulins Panel (IgG, IgA, IgM), Serum

  • Detect abnormal antibody protein patterns
  • Monitor immune system protein levels
  • Track unusual blood protein changes
$624
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained bone pain, fatigue, frequent infections, or if a prior blood test found unusual proteins in your blood. It helps identify and monitor abnormal antibody proteins (called M proteins or M components) that can be linked to certain immune system or bone marrow conditions. It's often used as a follow-up after protein electrophoresis showed something worth investigating further.

What's included in this test?

This panel combines immunofixation, which identifies specific abnormal antibody proteins by type, with quantitative measurement of your three main immunoglobulin classes. Together, these results give a fuller picture of how your immune system's antibody production is behaving, which is especially useful for spotting and tracking unusual protein patterns over time.

What happens after I get my results?

Your results will be available in your account, with each immunoglobulin value shown alongside its normal range and a plain-language explanation. If your results show an M protein or an abnormal immunoglobulin pattern, the report will outline what that means and suggest appropriate next steps, which may include retesting in a few months to track changes over time. You can download a standard lab report directly from your account at any time, and the trends feature lets you compare results across multiple tests to see how your levels are changing. If any value comes back significantly abnormal, seek medical care promptly to discuss the finding further.

How can I naturally support healthy immune function?
While immunoglobulin levels are largely driven by underlying immune activity rather than lifestyle alone, supporting general immune health can still help. Eating a balanced diet rich in fruits, vegetables, and lean protein, staying well hydrated, getting consistent sleep, and managing stress all support healthy immune function. Avoiding smoking and excessive alcohol use is also beneficial, since both can affect antibody production.
When will I get my results?
Results for this panel are typically ready within about 7 days of your sample being processed at the lab. Because immunofixation involves a detailed lab technique to identify specific protein types, it takes a bit longer than a standard blood test. You'll receive a notification as soon as your results are ready to view in your account.
Who should consider this test?
This test is a good option for people who had an abnormal protein electrophoresis result, those with a family history of plasma cell or bone marrow disorders, or anyone experiencing symptoms like persistent fatigue, bone pain, or recurring infections without a clear cause. It's also useful for ongoing monitoring if you've previously been found to have an M protein, to track whether levels are stable, rising, or falling over time.
What symptoms indicate I may need this test?
Common signs that may prompt this test include unexplained bone or back pain, ongoing fatigue or weakness, frequent or unusual infections, and unexplained weight loss. Some people are prescribed this test after a routine blood or urine test showed an abnormal protein pattern, even without obvious symptoms. If you're experiencing several of these signs together, it's worth having your immunoglobulin levels checked.
What does a high immunoglobulin level mean?
A high level in one specific immunoglobulin class, especially when it shows up as a distinct M protein on immunofixation, can indicate that a group of similar antibody-producing cells is multiplying more than expected. This pattern is worth monitoring closely and discussing further, and the report will describe which class is elevated. Retesting on a regular schedule is often recommended to see whether the level is stable or increasing.
What does a low immunoglobulin level mean?
Low immunoglobulin levels can mean your body isn't producing enough antibodies to fight off infections effectively, which might explain frequent colds or infections that take longer to clear. This can sometimes be related to nutrition, certain medications, or how your immune system is functioning overall. If your levels come back low, it helps to note how often you get sick and how you're recovering, and to retest to confirm the trend.
How often should I retest?
If your first result is normal and you have no ongoing symptoms, retesting isn't usually needed unless new symptoms appear. If you have an abnormal result, especially an M protein, retesting every 3 to 6 months is a common approach to track whether your levels are changing. Your lab report will include guidance on a suggested retesting timeline based on your specific results.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
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Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
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Fast & confidential, we never sell or share your data
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Demo results
Immunoglobulin G (IgG) 1850 mg/dL
Demo results
Low Normal High
1850 mg/dL

What this means

This IgG level is above the typical reference range, which can mean your body is producing more of this antibody type than usual. Combined with the immunofixation result, this pattern may point to a group of antibody-producing cells multiplying more than expected. This is worth monitoring closely with follow-up testing.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Immunofixation & Immunoglobulins Panel Blood Test

  • Detect abnormal antibody protein patterns
  • Monitor immune system protein levels
  • Track unusual blood protein changes
$624
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.