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IGFBP-2 blood test for metabolic, cancer risk, and cognitive health screening

IGFBP-2 Blood Test — Metabolic and Cancer Risk Marker

IGF Binding Protein-2 (IGFBP-2)

  • Screen for diabetes and obesity risk
  • Assess certain cancer growth markers
  • Track long-term memory and cognition risk
$414
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're concerned about your metabolic health, family history of certain cancers, or memory and cognitive changes as you age. It measures a protein called IGFBP-2 that plays a role in how your body handles blood sugar, fat storage, and cell growth. People exploring risk factors for diabetes, obesity, certain tumors, or dementia often use this test to get more insight into their health picture.

What happens after I get my results?

Your results will be available in your account, with each value's normal range clearly explained so you know exactly where you stand. Depending on whether your IGFBP-2 is high or low, simple next steps might include adjusting your diet, increasing physical activity, or retesting in a few months to track changes. A standard lab report is available to download directly from your account at any time. You can also use the trends feature to watch how your IGFBP-2 level changes over time, which is especially useful if you're making lifestyle changes.

How can I naturally support healthy IGFBP-2 levels?

Since low IGFBP-2 is linked to obesity and insulin resistance, maintaining a healthy weight through regular exercise and a balanced diet can help support healthy levels. Reducing added sugars and refined carbs may improve insulin sensitivity, which is connected to how your body regulates this protein. Getting consistent sleep and managing stress also support healthy metabolic and hormone balance overall. If you have concerns about cancer risk or cognitive health, staying active and eating a nutrient-rich diet are practical steps that support long-term brain and cellular health.

When will I get my results?
Results for this test are typically ready within about 7 days after your sample is collected at the lab. Once ready, you'll be able to view them securely in your online account. You'll get a notification so you know as soon as your report is available, and you can download it anytime afterward.
Who should consider this test?
This test may be worth considering if you have a personal or family history of certain cancers like glioma, prostate, breast, or ovarian cancer, since IGFBP-2 has been linked to tumor activity. It's also relevant if you're managing or at risk for obesity, type 2 diabetes, or metabolic syndrome. People noticing memory changes or wanting to understand their long-term cognitive health risk may also find this test useful, especially with a family history of dementia.
What symptoms might suggest I need this test?
You might consider this test if you're noticing unexplained weight gain, difficulty losing weight, or signs of insulin resistance like fatigue after meals or increased thirst. Memory lapses, brain fog, or a family history of Alzheimer's disease are other reasons some people look into this marker. A known diagnosis of certain cancers, or a strong family history of them, is another common reason people explore this test.
What is IGFBP-2 and why does it matter?
IGFBP-2 is a protein in your blood that helps carry and regulate insulin-like growth factors (IGFs), which influence how cells grow, how your body uses energy, and even brain health. It's especially high before birth and gradually decreases as we age. Because it's involved in metabolism, cell growth, and brain protection, doctors and researchers have studied it as a possible clue for conditions ranging from diabetes to certain cancers to dementia.
What does a high IGFBP-2 result mean?
A higher-than-normal IGFBP-2 level has been associated with certain cancers, since this protein is often elevated in tumors like glioma, prostate, and ovarian cancer, possibly contributing to how aggressively they grow. It has also been linked to a higher risk of cognitive decline and Alzheimer's disease in otherwise healthy older adults. If your result is high, it's worth looking at your full health picture, including any relevant family history or symptoms, and considering a retest to confirm the pattern.
What does a low IGFBP-2 result mean?
Lower IGFBP-2 levels have been linked to obesity, type 2 diabetes, and metabolic syndrome. This may reflect how your body is processing insulin and storing fat. If your level is low, focusing on weight management, regular exercise, and reducing sugar intake are practical starting points, and retesting later can help you see if those changes are making a difference.
How often should I retest IGFBP-2?
Since research on IGFBP-2 is still evolving and it's not a routine screening test, there's no universal retesting schedule. If you're making lifestyle changes to address weight, blood sugar, or metabolic health, retesting every 3 to 6 months can help you track meaningful trends. If you're monitoring it in the context of a known cancer or cognitive concern, more frequent monitoring may make sense based on your specific situation.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
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Fast & confidential, we never sell or share your data
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Demo results
IGF Binding Protein-2 (IGFBP-2) 215 ng/mL
Demo results
Low Normal High
215 ng/mL

What this means

This result falls below the typical reference range for IGFBP-2. Low levels have been associated with obesity, insulin resistance, and metabolic syndrome in research studies.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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IGFBP-2 Blood Test — Metabolic and Cancer Risk Marker

  • Screen for diabetes and obesity risk
  • Assess certain cancer growth markers
  • Track long-term memory and cognition risk
$414
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.