What's this test for?

This test is ideal if you're at higher risk for anal dysplasia, such as if you have a history of HPV infection, receptive anal intercourse, or a weakened immune system. It checks for active HPV infection in rectal tissue that could lead to abnormal cell changes. It's often used together with a Pap-like cytology test to get a fuller picture of anal health.

What's included in this test?

This test looks for HPV mRNA activity in rectal cells, which shows whether a high-risk HPV infection is actively producing proteins linked to cell changes. If the initial result is positive, it automatically reflexes to genotype testing for HPV 16 and 18/45, the strains most strongly linked to anal cancer risk. Together, these results help clarify not just whether HPV is present, but how concerning that infection may be.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what's normal and what's not for this test. If your result is positive, next steps typically include follow-up cytology or further evaluation to check for abnormal cell changes, so you can act early. A downloadable lab report is always available in your account, and you can track results over time using the trends feature if you retest in the future.

How can I naturally support immune clearance of HPV?

A strong immune system is your best natural defense against clearing HPV over time. Eating a nutrient-rich diet, getting enough sleep, managing stress, and avoiding smoking can all help your immune system work more effectively. Regular exercise and cutting back on alcohol may also support your body's ability to fight off the virus.

When will I get my results?

Results are typically ready within about 7 days of your lab visit. You'll receive a notification once they're posted to your secure online account. If the reflex genotyping is triggered, this may add a small amount of extra processing time before your final report is complete.

Who should consider this test?

This test is a good fit for people with a history of HPV, abnormal anal Pap results, or those in higher-risk groups such as men who have sex with men or individuals with weakened immune systems. It's also useful if you've had genital warts or other HPV-related conditions in the past. Talk through your personal risk factors to decide if regular screening makes sense for you.

What symptoms indicate I may need this test?

Many HPV infections cause no symptoms at all, which is why screening matters even if you feel fine. Some people notice anal itching, bleeding, discomfort, or visible warts, which are signs worth investigating. If you've had abnormal cytology results before, that's also a strong reason to test.

What does a positive HPV mRNA result mean?

A positive result means the test found active high-risk HPV infection in your rectal cells, which raises your risk for developing abnormal cell changes over time. It doesn't mean you have cancer, but it does mean closer monitoring is a smart next step. Follow-up genotyping and cytology help determine how you should proceed.

How often should I retest?

Retesting frequency depends on your risk factors and previous results, but many people in higher-risk groups test annually. If you've had a positive result before, more frequent monitoring may be recommended to track any changes. Using the trends feature in your account can help you and your care routine stay on schedule.

What should I do if my results are abnormal?

If your result is positive or shows a high-risk genotype, the recommended next step is usually a follow-up evaluation with anal cytology or a closer visual exam of the area. Avoid smoking and support your immune system in the meantime, since a healthy immune response helps clear infections faster. If you notice new symptoms like bleeding or pain, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

HPV Rectal Test - Anal Dysplasia Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

HPV Rectal Test for Anal Dysplasia Screening

HPV mRNA E6/E7, Rectal with Reflex to Genotypes, 16, 18/45

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

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HPV Rectal Test for Anal Dysplasia Screening

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

1,000,000+ blood tests later, here's what our customers say