What's this test for?

This test is ideal if you're experiencing unexplained joint pain, chronic inflammation, or other symptoms that could point to an autoimmune condition. It's also useful if you have a family history of autoimmune disease and want to understand your genetic risk. Many people use this test to get clarity on symptoms that haven't been explained by other testing.

What's included in this test?

This test looks at specific gene markers on the HLA-DRB1 gene, which plays a key role in how your immune system recognizes and responds to threats. Certain versions of this gene are strongly linked to autoimmune conditions like rheumatoid arthritis and type 1 diabetes, so knowing your genetic pattern can help explain your risk. High-resolution typing gives a more detailed, accurate read on your specific gene variants compared to standard testing.

What happens after I get my results?

Your results will be available in your account, with each value explained so you understand what it means. Since this is a genetic test, results don't change over time, but they can help guide conversations about ongoing symptom monitoring and lifestyle choices that support immune health. A standard lab report is available to download directly from your account. If you're tracking related symptoms or other lab work, you can use the trends feature to see the full picture over time.

How can I naturally support immune system balance?

Eating an anti-inflammatory diet rich in vegetables, omega-3 fats, and fiber can help support a balanced immune response. Regular sleep, stress management, and moderate exercise all play a role in keeping inflammation in check. Avoiding smoking and limiting processed foods are also simple steps that support long-term immune health.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. This timeframe reflects the detailed genetic analysis required for high-resolution typing. You'll get a notification as soon as your results are ready to view in your account.

Who should consider this test?

People with a family history of autoimmune disease, unexplained joint or inflammatory symptoms, or those wanting more information before starting certain treatments may benefit from this test. It's also relevant for people exploring bone marrow or organ transplant compatibility, since HLA typing plays a role there too. If autoimmune conditions run in your family, this test can offer useful genetic insight.

What symptoms indicate I may need this test?

Joint pain and stiffness, unexplained fatigue, skin rashes, or recurring inflammation can all be signs worth investigating with genetic testing. Digestive issues that come and go, along with a family history of autoimmune disease, are also common reasons people look into HLA-DRB1 typing. If you've had unexplained symptoms for a while without answers, this test may provide useful context.

What is HLA-DRB1 and why does it matter?

HLA-DRB1 is a gene that helps your immune system tell the difference between your own cells and outside invaders like viruses and bacteria. Certain variations of this gene are associated with a higher likelihood of developing autoimmune conditions such as rheumatoid arthritis, type 1 diabetes, and certain thyroid disorders. Understanding your specific gene type can help you and your care circle stay alert to early symptoms.

How often should I retest?

Since HLA-DRB1 typing looks at your genetic code, it doesn't change over your lifetime, so retesting typically isn't necessary once you've had this test done. Your result remains valid for life. If you're monitoring an actual autoimmune condition, separate blood tests for inflammation or specific antibodies would be more useful for ongoing tracking.

What should I do if my results show a higher-risk gene variant?

A higher-risk result doesn't mean you will definitely develop an autoimmune condition — it means your genetic makeup carries a higher statistical likelihood. Pay closer attention to early symptoms like joint pain, fatigue, or skin changes, and consider periodic screening for inflammation markers. Maintaining a healthy lifestyle with good sleep, diet, and stress management can help support your immune system regardless of genetic risk.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

HLA-DRB1 Typing Test - Autoimmune Risk Insight

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]