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HLA Class I antibody test for transplant candidates and organ donor compatibility screening

HLA Class I Antibody Test for Transplant Compatibility

HLA Antibody Identification, Class I

  • Screen for transplant rejection risk
  • Check donor tissue compatibility factors
  • Detect immune antibody sensitization levels
$1087
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're preparing for an organ or tissue transplant and need to check for antibodies that could cause your body to reject donor tissue. It's also useful if you've had a previous transplant, blood transfusion, or pregnancy, since these can trigger the immune system to develop antibodies against specific tissue markers. Identifying these antibodies ahead of time helps determine compatibility with potential donors.

What's included in this test?

This test looks for antibodies against Class I tissue markers, which are proteins found on almost all cells in your body. Detecting these antibodies matters because they can attack donor organ or tissue cells, leading to rejection after a transplant. Knowing which specific antibodies are present helps match you with a more compatible donor.

What happens after I get my results?

Your results will show up in your account along with a clear explanation of what a positive or negative antibody finding means. If antibodies are detected, next steps typically involve further compatibility testing or discussing timing with a transplant program before moving forward. You can download a standard lab report anytime from your account, and if you test again in the future, the trends feature lets you compare results side by side.

How can I naturally support immune balance?
While you can't change antibody levels through lifestyle alone, keeping your immune system balanced can support overall health during the transplant process. Eating a nutrient-rich diet, staying hydrated, getting consistent sleep, and avoiding unnecessary infections can help your body stay in the best shape possible. Avoiding smoking and excess alcohol is also recommended since both can stress the immune system further.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. This timeframe allows for the detailed antibody analysis required for this specialized test. You'll get a notification as soon as your results are available in your account.
Who should consider this test?
This test is a good fit for anyone on a transplant waiting list, anyone being evaluated as a potential organ or tissue donor, or anyone who has had a prior transplant, transfusion, or pregnancy and needs compatibility screening. It's also relevant if a previous transplant showed signs of rejection and the cause needs to be investigated.
What symptoms indicate I may need this test?
Unlike many blood tests, this one isn't ordered based on symptoms you feel day to day. Instead, it's used proactively before a transplant or after signs of organ rejection, such as unexplained fever, pain near a transplanted organ, or reduced organ function noticed through other testing. If you're experiencing any of these after a transplant, this test can help identify the cause.
What does a positive antibody result mean?
A positive result means your immune system has developed antibodies that recognize certain tissue markers as foreign, which raises the risk of rejecting a donor organ with matching markers. This doesn't mean a transplant is impossible, but it does mean more careful donor matching is needed. The report will detail which specific antibodies were found so this information can guide next steps.
What causes these antibodies to develop?
These antibodies commonly form after exposure to foreign tissue, which happens during pregnancy, blood transfusions, or a previous transplant. Your immune system reacts to these exposures the same way it would to any foreign substance, building a memory of it. This is why people with more of these exposures tend to have a higher chance of testing positive.
How often should I retest?
Retesting frequency depends on your individual transplant timeline, but many people on a waiting list are retested periodically, such as every few months, since antibody levels can change over time. If you experience a new triggering event, like a transfusion, retesting sooner is a good idea. Your transplant program's typical schedule can guide exactly when your next test should happen.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
HLA Class I Antibodies Negative
Demo results
Negative Positive
Negative

What this means

A negative result means no HLA Class I antibodies were detected in your blood sample. This is a favorable finding for transplant compatibility, since it suggests a lower risk of rejecting donor tissue that carries these markers. A positive result would mean antibodies are present and more careful donor matching would be needed.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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HLA Class I Antibody Test for Transplant Compatibility

  • Screen for transplant rejection risk
  • Check donor tissue compatibility factors
  • Detect immune antibody sensitization levels
$1087
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.