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HCV genotype and drug resistance test for patients managing hepatitis C treatment

Hepatitis C Genotype & Drug Resistance Blood Test

Hepatitis C Virus RNA Genotype with Reflex to HCV NS5a Drug Resistance

  • Identify your hepatitis C virus strain
  • Screen for antiviral treatment resistance
  • Guide your hepatitis C treatment plan
$2071
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you've already been diagnosed with hepatitis C and need to figure out which treatment will work best for you. It identifies the specific genotype (strain) of the hepatitis C virus in your blood and checks whether the virus has genetic changes that make it resistant to certain medications. This information helps guide which direct-acting antiviral drug is most likely to clear the infection effectively.

What's included in this test?

This test identifies which strain, or genotype, of hepatitis C you have, since different genotypes respond differently to different medications. It also checks for genetic mutations in a part of the virus called NS5A that can make certain treatments less effective, which is important for choosing a drug that will actually work against your specific virus.

What happens after I get my results?

Your results will appear in your online account, with a clear explanation of what your genotype result and any resistance findings mean. If a drug-resistant mutation is detected, the report explains what that means for treatment selection, and you can use this information when choosing your treatment plan. You can download a standard lab report directly from your account at any time, and if you get retested later, you'll be able to track your results over time using the trends feature.

How can I naturally support liver health during hepatitis C treatment?
While no natural remedy cures hepatitis C, you can support your liver by avoiding alcohol completely and limiting processed, fatty foods. Staying well-hydrated, eating plenty of fruits and vegetables, and getting regular moderate exercise can help your liver function better overall. Avoid unnecessary medications or supplements that stress the liver, like high-dose acetaminophen, unless you've checked they're safe for you.
When will I get my results?
Results for this test are typically available within about 7 days of your sample being processed at the lab. Genotype and resistance testing involves detailed genetic analysis, which takes a bit longer than a standard blood test. You'll receive a notification as soon as your results are ready to view in your account.
Who should consider this test?
This test is meant for people who already have a confirmed hepatitis C infection with a viral load of at least 2000 IU/mL, and who are preparing to start or adjust antiviral treatment. It's especially useful if a previous treatment didn't work, since resistance testing can reveal why. It's not a general screening test for people who haven't been diagnosed with hepatitis C yet.
What is hepatitis C genotype and why does it matter?
Hepatitis C isn't just one virus — it has several genetic variations called genotypes, numbered 1 through 6, each responding differently to treatment. Knowing your genotype helps match you to the antiviral medication most likely to clear the virus in the shortest amount of time. Some genotypes, like genotype 1, may need specific drug combinations that aren't necessary for others.
What does a drug resistance finding mean?
If your results show a resistance-associated mutation in the NS5A region, it means part of the virus has changed in a way that can make certain antiviral medications less effective. This doesn't mean treatment won't work, but it may mean a different medication or combination is needed. This finding is meant to guide smarter treatment selection, not to signal a treatment failure.
How often should I retest?
Retesting isn't typically needed unless your treatment isn't working as expected or your viral load doesn't drop the way it should. If you switch treatments or your first round of therapy doesn't clear the virus, retesting for genotype and resistance can help identify next steps. Your viral load is usually tested separately and more frequently to track treatment progress.
What should I do if my results show resistance?
If your results show a resistance mutation, the next step is choosing a treatment regimen that isn't affected by that specific mutation. Keep the report handy since it details exactly which mutation was found, which is useful for treatment planning. Continue avoiding alcohol and taking care of your liver while you finalize your treatment approach, and seek medical care promptly if you notice symptoms like yellowing skin or severe fatigue.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
HCV Genotype / NS5A Resistance Mutation Genotype 1a, No Resistance Detected
Demo results
No Resistance Detected Resistance Mutation Detected
Genotype 1a, No Resistance Detected

What this means

This result shows the hepatitis C virus is genotype 1a and no NS5A resistance mutations were found. This means standard antiviral treatments for genotype 1a should work effectively without needing adjustment. Not detecting resistance is a favorable finding for treatment planning.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Hepatitis C Genotype & Drug Resistance Blood Test

  • Identify your hepatitis C virus strain
  • Screen for antiviral treatment resistance
  • Guide your hepatitis C treatment plan
$2071
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.