What's this test for?

This test is ideal if you're being treated for hepatitis C genotype 3 and your previous treatment with NS5a inhibitor medications didn't work as expected. It checks whether your virus has developed mutations, like Y93H, that make it resistant to drugs such as daclatasvir or velpatasvir. Knowing this helps guide which antiviral medication is most likely to work for you.

What's included in this test?

This test looks specifically at the NS5a gene region of the hepatitis C genotype 3 virus to detect mutations that cause resistance to NS5a inhibitor drugs. Finding these mutations matters because they can make certain antiviral medications far less effective, so identifying them early helps steer you toward a treatment plan that has a real chance of clearing the virus.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a positive or negative resistance finding means. If a resistance mutation is found, a common next step is switching to a different class of antiviral medication or adjusting treatment duration. You can download a standard lab report from your account at any time, and if you get retested later, the trends feature lets you track changes over time.

How can I naturally support liver health during hepatitis C treatment?

While this test focuses on drug resistance rather than liver function, supporting your liver during treatment can still help. Cutting back on alcohol, eating a balanced diet low in processed fats, staying hydrated, and getting regular moderate exercise can ease the load on your liver. Avoid unnecessary over-the-counter medications or supplements that are hard on the liver, like high-dose acetaminophen, unless you've checked that they're safe for you.

When will I get my results?

Results for this test are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as your results are posted to your account, where you can view the detailed report.

Who should consider this test?

This test is best for people with genotype 3 hepatitis C who have already tried an NS5a inhibitor medication and didn't achieve a cure, or whose care plan includes checking for resistance before starting treatment. It's also useful if you're being considered for retreatment after a relapse.

What symptoms indicate I may need this test?

Hepatitis C itself often causes few noticeable symptoms, so this test is usually recommended based on treatment history rather than symptoms. However, if you've completed a course of NS5a inhibitor therapy and follow-up viral load testing shows the virus is still detectable, that's a strong sign this resistance test is worth doing.

What does a positive resistance result mean?

A positive result means specific mutations, such as Y93H, were found in the virus that can reduce how well NS5a inhibitor drugs work against it. This doesn't mean treatment is impossible, but it does mean a different combination of antiviral medications may be needed to effectively clear the virus. This information is typically used to adjust your treatment plan going forward.

What causes NS5a resistance mutations to develop?

These mutations usually develop when the hepatitis C virus is exposed to NS5a inhibitor drugs but isn't fully eliminated, allowing resistant viral strains to survive and multiply. This can happen if a previous treatment course didn't fully clear the virus, or in some cases mutations can exist naturally before treatment even starts. Incomplete adherence to a prescribed antiviral regimen can also increase the chance of resistance developing.

How often should I retest?

This is typically a one-time test done either before starting NS5a inhibitor treatment or after treatment fails to clear the virus. You generally wouldn't need to repeat it unless you go through another round of treatment that fails or your treatment plan changes significantly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Hep C Genotype 3 Resistance Test - Treatment Guide

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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