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Hepatitis C NS5a drug resistance test for patients starting genotype 1 HCV therapy

Hepatitis C NS5a Drug Resistance Test

Hepatitis C Viral RNA Genotype 1 NS5a Drug Resistance

  • Screen for hepatitis C drug resistance
  • Check treatment success before starting therapy
  • Guide antiviral medication choice confidently
$3382
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're living with hepatitis C genotype 1 and preparing to start treatment with certain antiviral medications. It checks whether your virus has genetic changes that could make specific drugs, like elbasvir plus grazoprevir, less effective. Knowing this ahead of time helps make sure your treatment plan actually works for your specific virus strain.

What's included in this test?

This test looks specifically at the NS5a gene region of the hepatitis C virus, genotype 1, to check for mutations linked to resistance against NS5a inhibitor medications. Understanding this helps determine whether certain antiviral combinations are likely to clear the virus effectively before you start treatment.

What happens after I get my results?

Your results will show up in your account, with an explanation of what each finding means in plain terms. If resistance-associated mutations are found, the report will explain what that means for treatment planning, and you can use that information when discussing next steps for your care. You can download a standard lab report from your account at any time, and if you're retested later, you can track results over time using the trends feature.

How can I naturally support liver health during hepatitis C treatment?
While no natural remedy treats hepatitis C itself, supporting your liver with a balanced diet, limiting alcohol, and staying hydrated can help your body handle treatment better. Regular, moderate exercise and getting enough sleep also support overall liver function and immune health. These steps work alongside treatment, not as a replacement for it.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. This timeframe allows for the detailed genetic analysis needed to detect resistance mutations accurately. You'll be notified as soon as your results are available in your account.
Who should consider this test?
This test is most relevant for people with confirmed hepatitis C genotype 1 infection who are about to start antiviral treatment, especially with elbasvir plus grazoprevir. It's also useful if a previous hepatitis C treatment didn't fully clear the virus, since resistance mutations can develop over time. Checking for these mutations beforehand helps guide which medication combination is most likely to succeed.
What symptoms indicate I may need this test?
Hepatitis C itself often has no obvious symptoms, so this test isn't based on symptoms but on your treatment plan. If you've been diagnosed with genotype 1 hepatitis C and are being considered for NS5a inhibitor therapy, this test is a recommended step regardless of how you feel. Fatigue, jaundice, or abdominal discomfort may prompt initial hepatitis C testing, but this specific test is about treatment planning, not diagnosis.
What is NS5a resistance and why does it matter?
NS5a is a protein the hepatitis C virus needs to multiply, and certain medications work by blocking it. Sometimes the virus develops mutations in the NS5a gene that make these blocking drugs less effective, which is called resistance. Testing for these mutations before treatment helps identify the right drug combination so treatment has the best chance of clearing the virus on the first try.
What does a positive resistance result mean?
A positive result means your virus carries mutations that may reduce the effectiveness of NS5a inhibitor medications like elbasvir, daclatasvir, or ledipasvir. This doesn't mean treatment won't work, but it may mean a different drug combination or longer treatment duration is a better fit. This information is meant to guide treatment selection, not cause alarm.
What should I do if my results show resistance mutations?
If mutations are found, the report will explain which drugs may be affected, and this information can be used to select an alternative treatment regimen better suited to your virus. It's helpful to keep a copy of your downloadable report for your records when discussing treatment options. Retesting isn't usually needed unless your treatment plan changes significantly or a later treatment attempt doesn't clear the virus.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
NS5a Resistance-Associated Variants Not Detected
Demo results
Not Detected Detected
Not Detected

What this means

A 'Not Detected' result means no known resistance mutations were found in the NS5a gene of your hepatitis C virus. This suggests that NS5a inhibitor medications, such as elbasvir plus grazoprevir, are likely to work well as part of your treatment plan.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

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Hepatitis C NS5a Drug Resistance Test

  • Screen for hepatitis C drug resistance
  • Check treatment success before starting therapy
  • Guide antiviral medication choice confidently
$3382
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.