What's this test for?

This test is ideal if you're currently being treated for hepatitis C genotype 1 and your treatment isn't working as expected, or if you're about to start a new antiviral regimen. It looks for specific viral mutations that can make certain hepatitis C medications less effective. This helps identify why a treatment might be failing or whether a planned medication is likely to work well for your specific virus.

What's included in this test?

This test checks the genetic makeup of hepatitis C genotype 1 to spot specific mutations in the virus's NS3 protease region. These mutations matter because they can make certain antiviral drugs, like grazoprevir, simeprevir, and paritaprevir, less effective at clearing the virus. Knowing this ahead of time helps guide which medications are more likely to succeed for you.

What happens after I get my results?

Your results will be available in your account, with an explanation of what each finding means and whether resistance mutations were detected. If mutations are found, the report outlines which medications may be less effective, so you can discuss alternative treatment options going forward. You can download the standard lab report anytime from your account, and if you get retested later, the trends feature lets you track any changes in resistance patterns over time.

How can I naturally support liver health during hepatitis C treatment?

While natural approaches can't replace antiviral treatment, you can support your liver by avoiding alcohol completely and limiting processed, fatty foods. Staying hydrated, eating plenty of vegetables, and getting regular moderate exercise can help your liver function better overall. Some people find milk thistle supplements helpful, but check with your pharmacist or care team about any interactions with your current medications.

When will I get my results?

Results for this specialized resistance test typically take about 7 days to process. This is longer than a standard blood test because the lab needs to analyze the virus's genetic sequence in detail. You'll receive a notification as soon as your results are ready to view in your account.

Who should consider this test?

This test is best for people with genotype 1 hepatitis C who have already tried protease inhibitor treatment without success, or anyone being considered for a simeprevir-based regimen. It's also useful if you want to understand upfront whether a planned medication is likely to work for your specific virus strain. This is a specialized test, not a routine screening tool.

What symptoms indicate I may need this test?

You typically wouldn't order this test based on symptoms alone, since hepatitis C itself often causes no obvious symptoms. Instead, this test becomes relevant if a previous antiviral treatment failed to clear the virus, or if your viral load isn't dropping the way it should during treatment. Fatigue, jaundice, or abnormal liver readings during treatment can also be a sign it's worth checking for resistance.

What is NS3 drug resistance and why does it matter?

NS3 is a protein the hepatitis C virus needs to multiply, and certain antiviral drugs work by blocking it. Sometimes the virus develops small genetic changes, called mutations, that let it dodge these drugs and keep multiplying anyway. Knowing whether these mutations are present helps you and your treatment team choose medications that are more likely to actually work.

What does a positive resistance result mean?

A positive result means specific mutations were found that can reduce how well certain protease inhibitor drugs work against your hepatitis C. This doesn't mean treatment won't work at all, but it does suggest that grazoprevir, simeprevir, or paritaprevir-based regimens may be less effective for you. This information is useful for choosing a different antiviral combination that isn't affected by these particular mutations.

How often should I retest for resistance mutations?

Retesting isn't something you'd do on a routine schedule like a cholesterol check. It generally makes sense to retest if a treatment regimen isn't clearing the virus as expected, or before switching to a new protease inhibitor-based medication. Your treatment plan and response to therapy should guide the timing rather than a fixed calendar.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Hepatitis C Genotype 1 Resistance - Treatment Guide Test

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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