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Specialized blood test for detecting heparin-induced platelet antibodies and clotting risk

Heparin Antibody Test with Reflex to Serotonin Release Assay

Heparin-Induced Platelet Antibody with Reflex to SRA, Unfractionated Heparin

  • Detect heparin-related platelet antibody reactions
  • Screen for dangerous blood clotting risk
  • Confirm results with automatic reflex testing
$632
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're currently on or recently received heparin (a blood thinner) and have developed an unexplained drop in platelet count or new blood clots. It helps figure out if your body has formed antibodies against heparin that are attacking your platelets, a condition called Heparin Induced Thrombocytopenia (HIT). If you've noticed unusual bruising, bleeding, or a clot after starting heparin therapy, this test can help identify the cause.

What happens after I get my results?

Your results will appear in your account with a plain-language explanation of what a positive or negative antibody result means. If the initial antibody screen is positive, this test automatically reflexes to a Serotonin Release Assay for further confirmation, so you'll see both results together with their reference ranges explained. Because this condition can be serious if a clot is developing, a positive result calls for prompt medical attention rather than waiting for a retest. You can download the full lab report anytime and use the trends feature to track results if you're tested again in the future.

What symptoms indicate I may need this test?

Watch for a sudden or unexplained drop in your platelet count while on or after heparin treatment, unusual bruising, or bleeding that doesn't fit your usual pattern. New blood clots, swelling in a limb, chest pain, or shortness of breath after heparin exposure are also warning signs. These symptoms typically appear 5 to 10 days after starting heparin, though they can occur sooner if you've had heparin before.

How can I naturally support healthy platelet function?
While antibody-related platelet drops need to be addressed medically rather than through lifestyle changes, you can support overall platelet and vascular health with a diet rich in vitamin K (leafy greens), vitamin C, and iron. Staying well hydrated and avoiding excess alcohol also helps your body maintain healthy clotting function. Avoid any additional heparin exposure until this issue is fully resolved, since re-exposure can trigger the same antibody response.
When will I get my results?
Results for this test are typically ready within about 7 days from when your sample is collected. If the initial screening antibody test comes back positive, the reflex Serotonin Release Assay adds extra processing time since it's only run when needed. You'll get a notification as soon as your results are posted to your account.
Who should consider this test?
This test is meant for people who are currently taking heparin, have taken it recently, or have had a heparin-based procedure and are now showing signs of a falling platelet count or new clotting. It's also useful if you've had a bad reaction to heparin in the past and need confirmation before any future treatment decisions. This is not a general screening test for the public — it's specific to heparin exposure and its complications.
What is Heparin Induced Thrombocytopenia and why does it matter?
Heparin Induced Thrombocytopenia (HIT) is a reaction where your immune system makes antibodies against a combination of heparin and a protein called platelet factor 4. These antibodies can activate platelets in a way that paradoxically increases clotting risk even though your platelet count is dropping. It matters because untreated HIT can lead to serious clots in the legs, lungs, or other organs, so catching it early changes how future treatment is managed.
What does a positive result mean?
A positive ELISA antibody result means your body has made antibodies against the heparin-platelet complex, but it doesn't confirm active disease on its own — that's why a reflex Serotonin Release Assay is performed to check if those antibodies are actually activating platelets. A positive result on both tests strongly suggests HIT and means heparin should be avoided going forward. If you get a positive result, seek medical care promptly since HIT can be linked to dangerous clotting.
What causes a false or misleading result on this test?
Taking ticagrelor (Brilinta) around the time of testing can cause a false negative on the Serotonin Release Assay portion of this test, so it's important to flag any medications you're taking when you order. Other blood thinners and recent transfusions can also interfere with accurate readings. If your result doesn't match your symptoms, retesting after clearing interfering medications may be recommended.
What should I do if my results are abnormal?
If your antibody screen and Serotonin Release Assay both come back positive, this is a sign of active or developing HIT and you should seek medical care right away, especially if you have symptoms like leg swelling, chest pain, or shortness of breath. Avoid any further heparin exposure until the issue is resolved. Keep a copy of your results to share for any future procedures that might involve blood thinners.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Heparin-Platelet Factor 4 (PF4) Antibody Negative
Demo results
Negative Positive
Negative

What this means

A negative result means no heparin-induced antibodies were detected, so a heparin-triggered platelet reaction is unlikely to be causing your symptoms. If you're still having unexplained bruising or clotting, other causes should be looked into. If antibodies are detected (positive), the sample automatically moves to a Serotonin Release Assay for confirmation.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Heparin Antibody Test with Reflex to Serotonin Release Assay

  • Detect heparin-related platelet antibody reactions
  • Screen for dangerous blood clotting risk
  • Confirm results with automatic reflex testing
$632
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.