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HBME-1 immunohistochemistry test for evaluating tissue samples for mesothelioma markers

HBME-1 Tissue Stain Test for Mesothelioma Evaluation

HBME-1, IHC without Interpretation

  • Screen tissue samples for mesothelioma markers
  • Clarify unclear biopsy tissue findings
  • Support informed next steps quickly
$632
First results as soon as overnight*

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Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're following up on a tissue biopsy and need specialized staining to help identify the type of cells present. It's typically ordered when there's a concern about mesothelioma or certain carcinomas, and more detailed information about a tissue sample is needed. This test is a technical lab procedure performed on an existing tissue sample rather than a routine blood draw.

What happens after I get my results?

Your results will be available in your account along with an explanation of what the staining pattern means. Because this is a specialized tissue stain rather than a simple number, next steps usually involve discussing the pattern in the context of your overall tissue biopsy findings. The standard lab report is downloadable from your account at any time, and you can revisit it later if you need to compare it against future testing. Since this test isn't typically repeated on a routine schedule, the trends feature is less relevant here than for standard bloodwork.

What symptoms indicate I may need this test?

This test is usually ordered after imaging or a biopsy has already raised concern about a growth or mass, rather than based on everyday symptoms alone. Signs that may lead to this kind of workup include unexplained chest pain, shortness of breath, persistent cough, or a mass found on a scan. If you've already had a biopsy and the tissue findings are unclear, this stain can help clarify what type of cells are involved.

How can I naturally support healthy tissue and cell health?
While this test itself is diagnostic and not something lifestyle changes can influence directly, supporting your body's overall health can help you feel your best during this process. Eating a balanced diet with plenty of vegetables, staying physically active, avoiding tobacco smoke and asbestos exposure, and getting enough sleep all support your body's natural defenses. Reducing stress and staying hydrated are also simple ways to support your overall well-being while you await results.
When will I get my results?
Results for this specialized stain typically take about 7 days to process, which is longer than routine bloodwork because it involves detailed lab work on tissue samples. You'll receive a notification once your results are ready to view in your account. If your timeline feels urgent, keep in mind that thorough analysis takes a bit more time than a standard test.
Who should consider this test?
This test is generally considered by people who already have a tissue sample from a biopsy and need further clarification about what the cells show. It's often used as a follow-up step rather than a first-line test. If your recent biopsy results were inconclusive or specialists are trying to rule out mesothelioma versus other conditions, this stain may be the recommended next step.
What is HBME-1 and why does it matter?
HBME-1 is a special stain used in the lab to highlight a marker found on the surface of certain cells, especially those involved in mesothelioma. It helps lab professionals tell the difference between mesothelioma and other types of tumors that can look similar under a microscope. This distinction matters because different conditions require very different next steps and treatment approaches.
What does a positive HBME-1 stain result mean?
A positive result means the cells in your tissue sample picked up the stain in a pattern often associated with mesothelioma, though it can also show up in some carcinomas. The exact pattern of staining, such as whether it appears on the cell membrane or inside the cell, gives clues about which condition is more likely. This result is typically considered alongside other stains and clinical information, not on its own.
What does a negative HBME-1 stain result mean?
A negative result means the specific marker this stain looks for wasn't found in the tissue sample, which can help rule out mesothelioma as a likely explanation. It doesn't rule out every possible condition, since a full picture usually requires looking at several markers together. Your full lab report will explain how this result fits with any other tests performed on the same sample.
What should I do if my results are unclear or concerning?
If your report shows findings that are hard to interpret or address, the report itself will explain what the pattern typically indicates. Because this test relates to a serious potential diagnosis, don't wait to seek medical care if you're also experiencing symptoms like worsening chest pain or breathing difficulty. Keep a copy of your downloadable report so it's easy to reference for any follow-up testing.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Fast & confidential, we never sell or share your data
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Demo results
HBME-1 (Immunohistochemistry Stain) Negative
Demo results
Negative Positive
Negative

What this means

A negative result means the tissue sample did not show the staining pattern associated with mesothelioma cells. This can help rule out mesothelioma as a likely cause of the findings, though it should be interpreted alongside other tissue markers.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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HBME-1 Tissue Stain Test for Mesothelioma Evaluation

  • Screen tissue samples for mesothelioma markers
  • Clarify unclear biopsy tissue findings
  • Support informed next steps quickly
$632
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.