What's this test for?

This test is ideal if you or someone in your care has a tissue biopsy that needs specialized evaluation for mesothelioma or certain carcinomas. It's typically ordered as a follow-up to an existing biopsy sample rather than something you request on its own. Pathologists use this stain to help clarify what type of abnormal cells are present in the tissue.

What's included in this test?

This is a single specialized stain (HBME-1) applied to a tissue sample, along with a pathologist's written interpretation of the staining pattern. The stain helps distinguish mesothelial-origin cells from other cell types, which matters because different cell types point to very different underlying conditions and next steps.

What happens after I get my results?

Your results will be available in your account, with the pathologist's interpretation explaining what the staining pattern means for your tissue sample. Next steps depend heavily on the findings, so the report will outline what, if anything, should happen next, such as additional testing on the same sample. You can download the full lab report from your account at any time, and if further testing is ever needed, you can track results over time using the trends feature.

How can I naturally support healthy tissue and immune function?

While this test itself doesn't have lifestyle inputs since it's performed on an already-collected tissue sample, staying generally healthy can support your body while you wait on results. Eating a balanced diet rich in fruits, vegetables, and lean protein helps your immune system function well. Avoiding smoking and limiting exposure to asbestos or other airborne irritants is especially important if mesothelioma is a concern. Regular gentle exercise and good sleep also support overall immune health.

When will I get my results?

Results are typically ready within about 7 days of your tissue sample being processed. Specialized stains like this one require careful lab handling and pathologist review, which is why the turnaround is longer than a standard blood test. You'll receive a notification as soon as your report is ready to view in your account.

Who should consider this test?

This test is typically considered for people who already have a tissue biopsy pending evaluation, especially when mesothelioma or a related carcinoma is suspected. It's most relevant if you have a history of asbestos exposure, unexplained chest or abdominal symptoms, or an existing mass that needs to be characterized. This is usually ordered as part of a broader diagnostic workup rather than a standalone screening test.

What symptoms might lead someone to need this test?

Symptoms like persistent chest pain, shortness of breath, unexplained fluid buildup around the lungs or abdomen, or a persistent cough can prompt a tissue biopsy that this stain would then help evaluate. A history of long-term asbestos exposure combined with these symptoms often raises the concern that leads to this type of specialized testing. If you're experiencing any of these symptoms, especially with a known exposure history, getting evaluated promptly is important.

What does a positive HBME-1 staining result mean?

A positive result means the cells in your tissue sample show a staining pattern consistent with mesothelial origin, which raises the possibility of mesothelioma. However, this stain isn't perfectly specific, since some carcinomas can also show positive staining, though usually in a different pattern. Your report will explain the specific pattern seen and how it compares to typical mesothelioma versus carcinoma results.

What does a negative HBME-1 result mean?

A negative result means the cells tested did not show the staining pattern typically associated with mesothelial origin, which makes mesothelioma less likely based on this marker alone. It doesn't rule out other conditions, since pathologists usually look at a panel of several markers together rather than just one. Your report will note whether any additional stains or tests are recommended based on this finding.

What should I do if my results raise concerns?

If your report indicates findings that need urgent attention, seek medical care right away to discuss next steps and any additional testing. For most situations, the report will explain whether follow-up testing on the same tissue sample is recommended. Keeping a copy of your downloadable report is helpful if you need a second opinion or additional pathology review.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

HBME-1 IHC Test - Mesothelioma Tissue Evaluation

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]