What's this test for?

This test is ideal if you're experiencing bloating, stomach pain, diarrhea, or fatigue after eating foods with wheat or gluten. It looks at how your immune system reacts to gluten, which can help you understand if gluten might be contributing to your digestive discomfort. Many people use this test to get more clarity before making major changes to their diet.

What's included in this test?

This test measures your body's IgG4 immune response specifically to gluten, a protein found in wheat, barley, and rye. Checking this immune marker matters because elevated levels may point to a delayed food sensitivity reaction, which is different from a classic wheat allergy and often causes less obvious, longer-lasting symptoms.

What happens after I get my results?

Your results will show up in your account with the normal range explained so you can see exactly where your number falls. If your result suggests a reaction to gluten, a simple next step is to try reducing gluten in your diet for a few weeks and see if your symptoms improve, then retest later to track changes. You can download a standard lab report from your account at any time, and the trends feature lets you compare this result to future tests over time.

How can I naturally support gluten digestion?

If gluten seems to bother you, try gradually cutting back on wheat, barley, and rye and swapping in naturally gluten-free grains like rice, quinoa, or oats labeled gluten-free. Eating smaller, simpler meals and adding probiotic-rich foods like yogurt or kefir can also support gut comfort. Keeping a simple food and symptom journal helps you notice patterns before and after removing gluten.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as your report is available in your account, so there's no need to call or follow up.

Who should consider this test?

This test is a good fit for anyone who notices digestive discomfort, bloating, or fatigue after eating bread, pasta, or other wheat-based foods. It's also useful for people who suspect a gluten sensitivity but haven't been able to pin down the cause of their symptoms. If you're considering cutting gluten from your diet and want some data first, this test can help guide that decision.

What symptoms indicate I may need this test?

Common signs include bloating, gas, stomach cramps, diarrhea or constipation, fatigue, brain fog, and skin issues like rashes after eating gluten-containing foods. Some people also notice joint pain or headaches that seem to follow meals with bread, pasta, or baked goods. If these symptoms show up repeatedly after similar meals, it may be worth checking your gluten response.

What does a high IgG4 to gluten result mean?

A higher result suggests your immune system is producing more antibodies in response to gluten exposure, which some people associate with sensitivity symptoms like bloating or fatigue. It doesn't necessarily mean you have celiac disease, since this is a different kind of immune response. A practical next step is trying a short trial without gluten and noting whether your symptoms ease up.

What causes a high IgG4 response to gluten?

Frequent or regular exposure to gluten-containing foods can lead to a stronger measured antibody response over time. Some people naturally produce more of this antibody type without any symptoms at all, since it can simply reflect how much gluten they eat. Genetics and overall gut health can also play a role in how your immune system responds to gluten.

How often should I retest?

If you make dietary changes based on your first result, retesting after 8 to 12 weeks of consistent changes can help you see if your levels or symptoms have shifted. If your levels are already normal and you're not having symptoms, yearly testing is usually enough unless something changes. Retesting sooner makes sense if new symptoms show up after changing your diet.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Gluten IgG4 Test - Check Gluten Sensitivity

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]