What's this test for?

This test is ideal if you're experiencing unexplained fatigue, an enlarged spleen or liver, easy bruising, bone pain, or low blood counts that haven't been explained by other causes. It's also useful if you have a family history of Gaucher disease or Ashkenazi Jewish ancestry, since this population has a higher chance of carrying related gene changes. This test measures a specific substance in your blood that builds up when the body can't break down certain fats properly.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what the normal range is and where your value falls. If your level is elevated, next steps typically include additional confirmatory testing and lifestyle adjustments like monitoring for bruising, bone pain, or fatigue while you sort out further care. You can download a standard lab report straight from your account at any time, and if you retest later, the trends feature lets you track how your levels change over time. If your result is very high or comes with severe symptoms like extreme fatigue or bleeding, seek medical care promptly.

What symptoms indicate I may need this test?

Common signs include an enlarged spleen or liver, unexplained bruising or bleeding, chronic fatigue, bone pain or fractures, and low platelet or red blood cell counts. Some people also notice slower growth in childhood or neurological symptoms like difficulty with eye movements in more severe cases. If you have several of these symptoms together, especially with a family history, this test can help clarify what's going on.

How can I naturally support healthy fat metabolism?

While Gaucher disease itself is genetic and can't be fixed with lifestyle changes alone, supporting your body's overall metabolism helps manage symptoms. Staying physically active in ways that don't stress your bones, eating a balanced diet rich in anti-inflammatory foods, and getting enough vitamin D and calcium can support bone health. Avoiding excess alcohol and maintaining a healthy weight also reduces stress on your liver and spleen.

When will I get my results?

Results are typically ready within about 7 days of your blood draw. You'll get a notification once they're posted to your account, where you can view the values along with what they mean. This turnaround gives the lab enough time to run this specialized biomarker test accurately.

Who should consider this test?

People with unexplained enlarged spleen or liver, low blood counts, bone pain, or a family history of Gaucher disease are good candidates. It's also relevant for those of Ashkenazi Jewish descent, since this biomarker-related condition is more common in that population. Anyone who has a sibling or parent diagnosed with Gaucher disease may also want to check their own levels.

What is Lyso-Gb1 and why does it matter?

Lyso-Gb1 (glucosylsphingosine) is a substance that builds up in the blood when the body can't properly break down a fat called glucocerebroside. It's considered one of the most reliable markers for detecting and monitoring Gaucher disease, a condition where this fat accumulates in organs like the spleen, liver, and bone marrow. Tracking this marker helps show whether the underlying condition is active or progressing.

What does a high Lyso-Gb1 level mean?

A high level suggests that fatty substances are building up in your body faster than they can be broken down, which is a hallmark of Gaucher disease. The higher the number, the more active the disease process may be, and it often correlates with more noticeable symptoms like organ enlargement or bone problems. This finding usually calls for further confirmatory testing to understand the full picture.

How often should I retest?

If you're being monitored for Gaucher disease or tracking treatment progress, retesting every 6 to 12 months is common, though this can vary based on your specific situation. If your first result was normal but you have symptoms or family history, retesting isn't usually needed unless new symptoms appear. Using the trends feature in your account makes it easy to compare results over time.

What should I do if my results are abnormal?

If your Lyso-Gb1 level comes back elevated, don't panic — this marker alone doesn't diagnose Gaucher disease, but it does suggest further testing is worthwhile. Keep a record of any symptoms like fatigue, bruising, or bone pain to discuss during follow-up testing. If you experience severe symptoms such as significant bleeding, extreme fatigue, or intense bone pain, seek medical care right away.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Lyso-Gb1 Test - Gaucher Disease Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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