What's this test for?

This test is ideal if you're experiencing unexplained muscle stiffness, painful spasms, balance problems, or coordination issues that haven't been explained by other causes. It checks for GAD65 antibodies, which are linked to rare neurological conditions like Stiff-Person syndrome, cerebellar ataxia, and certain types of encephalitis. It's often used when symptoms are progressive or severe and a clearer answer is needed about what might be causing them.

What's included in this test?

This test measures one specific marker: GAD65 antibodies. It matters because these antibodies attack an enzyme involved in nerve signaling, and elevated levels are strongly associated with specific autoimmune neurological conditions, making this a targeted way to investigate certain nerve and muscle symptoms.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a normal versus positive result means for GAD65 antibodies. If your result is positive, the report will explain what that could mean and what kinds of next steps people typically consider, including further evaluation for neurological symptoms. If your result is negative but symptoms continue or worsen, it's a good idea to keep track of changes and consider retesting or additional workup. You can download the full lab report anytime and use the trends feature to track any future related testing over time.

How can I naturally support nerve and muscle health?

While GAD65-related conditions require targeted management, some everyday habits can support overall nerve and muscle function. Regular gentle stretching and low-impact movement, such as walking or swimming, can help ease muscle stiffness. Eating a balanced diet rich in B vitamins, magnesium, and antioxidants supports nerve health, and prioritizing good sleep helps your body manage stress-related muscle tension.

When will I get my results?

Results for this test are typically ready within about 7 days after your sample is collected. You'll get a notification once your report is available in your account. Because this is a specialized antibody test, it can take a bit longer than routine bloodwork to process.

Who should consider this test?

This test is a good fit for people with ongoing, unexplained muscle stiffness or spasms, difficulty with balance and coordination, or symptoms suggestive of an autoimmune nerve condition. It's also useful for those with a family history of autoimmune conditions who are experiencing new neurological symptoms. If symptoms are sudden or severe, seeking immediate medical care is the safer first step rather than waiting for test results.

What symptoms indicate I may need this test?

Common symptoms that might prompt this test include progressive muscle rigidity (especially in the trunk and limbs), painful muscle spasms triggered by stress or touch, difficulty walking or a loss of balance, and unexplained cognitive or behavioral changes. Some people also experience seizures or memory problems if encephalitis is involved. These symptoms are relatively rare, so this test is usually considered after more common causes have been ruled out.

What does a high GAD65 antibody result mean?

A high or positive result means your immune system may be producing antibodies that interfere with normal nerve signaling, which is associated with conditions like Stiff-Person syndrome, cerebellar ataxia, or autoimmune encephalitis. This doesn't diagnose a specific condition on its own but is an important piece of the puzzle when paired with your symptoms. If your result is positive, especially alongside significant symptoms, prompt follow-up care is recommended.

What causes elevated GAD65 antibodies?

Elevated GAD65 antibodies happen when the immune system mistakenly targets an enzyme called glutamic acid decarboxylase, which plays a role in nerve communication. This autoimmune response is also seen in some people with type 1 diabetes, though at different levels than those seen in neurological syndromes. The exact trigger for this immune reaction isn't fully understood, but it's thought to involve a combination of genetic and environmental factors.

What should I do if my results are abnormal?

If your GAD65 result comes back positive, it's important to take it seriously, especially if you're having ongoing neurological symptoms like stiffness, spasms, or balance issues. Keep a record of your symptoms and how they change over time, and seek prompt medical evaluation to discuss what a positive result means for you. If symptoms are severe or rapidly worsening, go to an emergency room rather than waiting.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

GAD65 Antibody Test - Neurological Symptom Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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