What's this test for?

This test is ideal if you or someone you love has been diagnosed with acute myeloid leukemia (AML) and needs to understand the specific genetic makeup of the disease. It looks for changes in the FLT3 gene that can affect how aggressive the leukemia is and how well it may respond to certain targeted treatments. This information helps guide treatment decisions and gives a clearer picture of what to expect going forward.

What's included in this test?

This test looks specifically at the FLT3 gene for two main types of changes: internal tandem duplications (ITD) and point mutations in the tyrosine kinase domain (TKD). These particular changes matter because they cause the FLT3 protein to stay switched on all the time, which can drive leukemia cells to grow and divide out of control. Knowing which type of mutation is present, and how much of it, helps explain how aggressive the disease may be and whether certain targeted therapies could be effective.

What happens after I get my results?

Your results will be available in your account, with each part of the report explained in plain language so you understand what was found. Because this is a specialized genetic test tied to leukemia treatment planning, the report will indicate whether a FLT3 mutation was detected and what type, which is information that should be acted on quickly given the urgency of AML care. You can download the full lab report from your account at any time, and if repeat testing is needed to monitor mutation status over the course of treatment, you can track those results over time using the trends feature. If your results show a mutation associated with poor prognosis or rapid progression, seek medical care promptly to discuss next steps.

What is FLT3 and why does it matter?

FLT3 is a gene that makes a protein involved in helping certain blood-forming cells grow and mature normally. When FLT3 develops specific mutations, it can get stuck in an "on" position, causing abnormal cells to multiply too quickly, which is a hallmark of acute myeloid leukemia. Testing for these mutations matters because it's one of the most common genetic changes found in AML, showing up in roughly a quarter to a third of cases, and it directly impacts treatment planning.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed. Since this test involves detailed genetic analysis, the timeline reflects the complexity of the work being done in the lab. You'll be notified as soon as your results are posted to your account, where you can view the full breakdown of findings.

Who should consider this test?

This test is generally considered for individuals who have already been diagnosed with, or are strongly suspected of having, acute myeloid leukemia. It's especially relevant for anyone whose care team is trying to determine the most effective treatment path, since FLT3 status can influence eligibility for targeted therapy options. People being monitored for relapse after AML treatment may also have a reason to consider repeat testing.

What symptoms indicate I may need this test?

Symptoms like persistent fatigue, unexplained bruising or bleeding, frequent infections, fever, and unexplained weight loss can sometimes point toward a blood-related condition like AML. If you've already had blood work showing abnormal cell counts, this test can add valuable detail about the underlying genetics. Because these symptoms can have many causes, it's important to seek medical care promptly if they persist so the right diagnostic path can be identified.

What does a high mutant allelic ratio mean?

A high mutant allelic ratio (above 0.5) means a larger proportion of the leukemia cells carry the FLT3 mutation, which is linked to a higher chance of relapse and a more challenging prognosis. On the flip side, patients with this profile are also often more responsive to FLT3-targeted therapies. This number is one piece of a bigger picture used to plan the most appropriate treatment approach.

How often should I retest?

Retesting frequency really depends on where someone is in their treatment journey, since FLT3 status can be checked at diagnosis and again if there are signs of relapse. Many people are retested after completing treatment phases to confirm the mutation is no longer detectable, or periodically during ongoing monitoring. Because AML can change quickly, seek medical care promptly to determine the right retesting schedule for your specific situation.

What should I do if my results are abnormal?

If your results show a FLT3 mutation, especially with a high allelic ratio, it's important to seek medical care promptly since this can affect how quickly treatment decisions need to be made. Bring your full report so the type and level of mutation can be factored into the treatment plan. Staying on top of follow-up testing and monitoring over time is also a key part of managing this condition.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

FLT3 Mutation Analysis - AML Prognosis & Treatment

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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