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FISH test for BCL6 gene rearrangement in suspected non-Hodgkin lymphoma cases

BCL6 Gene Rearrangement Test for Lymphoma Diagnosis

FISH, NHL, BCL6 3q27 Rearrangement

  • Detect specific lymphoma gene changes
  • Screen for BCL6 chromosome rearrangement
  • Assess B-cell lymphoma subtype details
$1920
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're being evaluated for non-Hodgkin lymphoma or you've already been diagnosed and need more detail about the specific type. It looks for a change in the BCL6 gene that shows up in certain B-cell lymphomas, including diffuse large cell lymphoma, follicular lymphoma, and marginal zone lymphoma. This information helps explain how aggressive the disease may be and what treatment approach makes sense.

What's included in this test?

This test specifically looks for rearrangements of the BCL6 gene located at chromosome position 3q27. This single, targeted analysis matters because BCL6 changes are found in up to 30% of diffuse large cell lymphoma cases and also appear in follicular and marginal zone B-cell lymphomas, so identifying it helps characterize the disease more precisely.

What happens after I get my results?

Your results will be available in your account along with an explanation of what a positive or negative finding means for this specific gene rearrangement. Because this is a specialized test tied to a cancer diagnosis, next steps typically involve sharing the report with your treatment team so it can guide therapy decisions rather than routine retesting at home. A standard lab report is available to download directly from your account at any time. If you've had related testing before, you can use the trends feature to keep a record of your results over time.

How can I naturally support my immune system during lymphoma evaluation?
While a gene rearrangement test result itself can't be changed through lifestyle, supporting your overall immune health can help you feel your best during evaluation and treatment. Eating a balanced diet with plenty of fruits, vegetables, and lean protein, staying well hydrated, getting regular sleep, and avoiding smoking or excess alcohol are all simple steps that support your body. Gentle movement like walking, when you feel up to it, can also help energy and mood.
When will I get my results?
Results for this specialized FISH test typically take about 7 days to process, since it involves detailed genetic analysis in the lab. You'll be notified as soon as your report is ready to view in your account. If your situation feels urgent, reach out to have your sample and results expedited when possible.
Who should consider this test?
This test is generally considered when someone has been diagnosed with, or is being worked up for, a B-cell non-Hodgkin lymphoma such as diffuse large cell, follicular, or marginal zone lymphoma. It's most useful as part of a broader diagnostic picture rather than a first step, so it's typically ordered alongside other pathology findings.
What symptoms indicate I may need this test?
Symptoms that often lead to lymphoma testing include swollen lymph nodes that don't go away, unexplained weight loss, night sweats, persistent fatigue, and recurring fevers. If you've noticed a lump that keeps growing or these symptoms together, it's worth getting evaluated. This FISH test is usually used after initial lymphoma testing to get more specific genetic information.
What is a BCL6 gene rearrangement and why does it matter?
BCL6 is a gene that normally helps control how certain immune cells grow and mature. When it gets rearranged, or moved to an abnormal position on the chromosome, it can cause cells to grow out of control, which is linked to several types of B-cell lymphoma. Finding this rearrangement helps show what specific type of lymphoma is present and can inform how aggressive treatment needs to be.
What does a positive result mean?
A positive result means the BCL6 gene rearrangement was detected in the tested cells, which supports a diagnosis of a B-cell lymphoma subtype where this change is common. This finding is usually combined with other lab and pathology results to build a complete picture of the disease. It does not by itself determine outlook, since many people with this rearrangement respond well to standard treatment.
What should I do if my results are abnormal?
If your result comes back positive for the BCL6 rearrangement, the most important step is to bring this report into your ongoing treatment planning so it can be factored in alongside your other diagnostic information. Keep a copy of the downloadable report for your records and any future comparisons. If you experience worsening symptoms like rapid lymph node growth, high fevers, or severe fatigue, seek medical care promptly.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

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Demo results
BCL6 (3q27) Gene Rearrangement Negative
Demo results
Negative (Not Detected) Positive (Detected)
Negative

What this means

A negative result means no BCL6 gene rearrangement was found in the sample tested. This suggests this particular genetic change is not contributing to the lymphoma being evaluated, though other genetic markers may still be relevant. Your full diagnostic picture should be considered together with this result.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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BCL6 Gene Rearrangement Test for Lymphoma Diagnosis

  • Detect specific lymphoma gene changes
  • Screen for BCL6 chromosome rearrangement
  • Assess B-cell lymphoma subtype details
$1920
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.