What's this test for?

This test is ideal if you're experiencing unexplained high eosinophil counts (a type of white blood cell) on a recent blood count and your results team wants to check for rare genetic changes tied to certain blood and immune system disorders. It's also useful if you've already been diagnosed with a myeloproliferative or eosinophilic condition and need more detail on what's driving it. This isn't a first-line test, but it can help clarify a confusing blood picture.

What's included in this test?

This panel uses a special genetic technique called FISH to look for rearrangements in three genes involved in cell growth signaling. These particular genes are grouped together because when any one of them gets scrambled through a chromosome swap, it can overactivate a growth switch inside blood cells, leading to the kind of eosinophil overgrowth seen in certain rare blood conditions. Detecting which gene is involved matters because it points toward specific treatment paths.

What happens after I get my results?

Your results will appear in your online account, with an explanation of what a positive or negative finding for each gene rearrangement means. If a rearrangement is found, the next step is usually further specialized testing to guide treatment options, since some of these changes respond well to targeted therapies. If your results are negative but your eosinophil counts remain high, retesting or additional bloodwork may be worth considering down the road. You can download the full lab report anytime and track any related bloodwork over time using the trends feature in your account.

When will I get my results?

Results for this test are typically available within about 7 days of your sample being processed at the lab. This type of genetic testing takes a bit longer than standard bloodwork because it involves detailed chromosome analysis. You'll receive a notification and can view your report directly in your account once it's ready.

Who should consider this test?

This test is best suited for people who have persistently high eosinophil counts without an obvious cause like allergies or parasites. It's also relevant for anyone already being evaluated for a rare blood or bone marrow condition where a genetic cause is suspected. If your recent blood work flagged unexplained eosinophilia, this can be a useful follow-up step.

What symptoms indicate I may need this test?

Common signs that might lead to this test include unexplained fatigue, skin rashes, breathing issues, or swelling that doesn't have a clear cause, especially when paired with high eosinophil counts on a blood count. Some people also notice enlarged lymph nodes or an enlarged spleen. These symptoms alone don't confirm anything, but combined with abnormal bloodwork they're a reason to dig deeper.

What is eosinophilia and why does it matter?

Eosinophilia simply means you have more eosinophils, a type of white blood cell, than normal in your blood. In most cases it's caused by common things like allergies or infections, but in rare cases it signals an underlying blood cell disorder involving genetic changes like the ones this test looks for. Figuring out the cause matters because the treatment approach is very different depending on what's driving it.

What does a positive result for a gene rearrangement mean?

A positive result means one of the three genes tested (PDGFRA, PDGFRB, or FGFR1) has been rearranged, which can overactivate the growth signal in your blood cells. This finding helps confirm a specific type of rare blood condition and points toward whether targeted therapies might work well for you. It's an important piece of information but works best alongside your full clinical picture.

How often should I retest?

This isn't a routine test you'd repeat on a regular schedule; it's typically done once to clarify a diagnosis. If you're being monitored for treatment response after starting therapy, your results team may recommend periodic retesting to track whether the genetic marker changes over time. Otherwise, this test is usually a one-time diagnostic step.

What should I do if my results are abnormal?

If a gene rearrangement is detected, it's a good idea to pursue further evaluation to confirm the diagnosis and explore treatment options, since some of these conditions respond well to specific targeted medications. Keep a copy of your report handy since it contains details that any follow-up testing will build on. If you notice worsening symptoms like severe fatigue, breathing trouble, or swelling in the meantime, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Eosinophilia FISH Panel - PDGFRA, PDGFRB, FGFR1 Genes

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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