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FISH MDM2 test for diagnosing liposarcoma and other soft tissue tumors

MDM2 Amplification FISH Test for Soft Tissue Tumors

FISH, MDM2 12q15/CEP 12

  • Classify soft tissue tumor types accurately
  • Detect genetic markers linked to liposarcoma
  • Support pathology diagnosis for tumor samples
$2122
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you have a soft tissue tumor that needs further classification to determine whether it's benign or cancerous. It helps distinguish conditions like lipomas from liposarcomas by looking at genetic changes in tumor cells. Your specimen would typically come from a biopsy or surgical sample already collected for pathology review.

What's included in this test?

This test looks specifically at the MDM2 gene and a reference marker called CEP12 using a technique called FISH, which lets lab scientists see genetic changes directly in tumor cells. Comparing these two markers helps determine whether the MDM2 gene has extra copies, a pattern strongly associated with certain soft tissue cancers rather than benign growths. This distinction matters because it directly impacts how a tumor is diagnosed and managed.

What happens after I get my results?

Your results will appear in your account along with an explanation of what a positive or negative finding means for MDM2 gene amplification. If the result shows gene amplification, the next step is usually additional pathology workup to determine the specific tumor type and appropriate treatment plan. A standard lab report is available for download directly from your account, and you can track any related results over time using the trends feature. If your result suggests a serious finding, consider seeking medical care promptly to discuss next steps.

How can I naturally support healthy cell function?
While no natural remedy can treat or prevent genetic changes like MDM2 amplification, general habits such as eating a nutrient-rich diet, avoiding tobacco, and limiting alcohol support your body's overall ability to repair and manage cell damage. Regular physical activity and adequate sleep also support healthy immune function, which plays a role in the body's surveillance against abnormal cells. These habits are supportive, not diagnostic or curative, so they should be paired with appropriate follow-up testing. Always continue with any recommended monitoring or additional evaluation regardless of lifestyle changes.
When will I get my results?
Results for this test are typically ready within about 7 days after your sample is received at the lab. FISH testing requires careful lab processing time since it involves examining genetic material directly in cells, which is why it takes a bit longer than routine blood work. You'll be notified as soon as your results are available in your account.
Who should consider this test?
This test is generally considered when a soft tissue mass or tumor has already been identified and pathology needs more detail to classify it accurately. It's especially useful for tumors that look like they could be either a benign lipoma or a more aggressive liposarcoma under the microscope. People with a known or suspected soft tissue tumor undergoing diagnostic workup are the main candidates for this specific test.
What symptoms might lead someone to need this test?
A soft tissue lump or mass that is growing, painless but persistent, or found deep in muscle tissue often prompts this kind of testing after imaging and biopsy. Symptoms like unexplained swelling, a firm mass under the skin, or a growth that doesn't resolve on its own are common reasons doctors pursue further tissue analysis. This test itself doesn't diagnose symptoms directly; it's used after a tumor sample has already been collected.
What is MDM2 amplification and why does it matter?
MDM2 is a gene that, in normal amounts, helps regulate a protein called p53 which controls how cells grow and divide. When there are too many copies of MDM2 (amplification), it can interfere with the body's normal cancer-suppressing processes, allowing abnormal cells to grow unchecked. This is why finding MDM2 amplification in a tumor sample is an important clue in diagnosing certain cancers like liposarcoma.
What does a positive MDM2 amplification result mean?
A positive result means the tumor cells show extra copies of the MDM2 gene, which is a pattern commonly seen in well-differentiated and dedifferentiated liposarcoma rather than benign fatty tumors. This finding helps guide how the tumor is classified and what treatment approach may be most appropriate. It's an important piece of the overall diagnostic picture, not a standalone diagnosis.
What should I do if my results show gene amplification?
If your results show MDM2 amplification, the most important next step is to pursue further evaluation to fully characterize the tumor type and plan appropriate care. Keep a copy of your lab report handy, as it will likely be needed for any follow-up pathology or treatment planning. Don't delay follow-up care if your results indicate a potentially serious finding.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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Get lab order in minutes, results come overnight*
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Demo results
MDM2 Gene Amplification (FISH) Negative
Demo results
Negative (No Amplification) Positive (Amplification Detected)
Negative

What this means

A negative result means the tumor cells tested do not show extra copies of the MDM2 gene, which is more consistent with a benign soft tissue growth like a lipoma. A positive result would indicate gene amplification, a pattern seen in liposarcoma and some other cancers. This result is one piece of a larger pathology evaluation, not a standalone diagnosis.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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MDM2 Amplification FISH Test for Soft Tissue Tumors

  • Classify soft tissue tumor types accurately
  • Detect genetic markers linked to liposarcoma
  • Support pathology diagnosis for tumor samples
$2122
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.