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FISH test for MALT lymphoma diagnosis in patients with suspected marginal zone lymphoma

MALT Lymphoma FISH Test with BIRC3/MALT1 Reflex

FISH, MALT Lymphoma, MALT1, rea18q21 with Reflex to API2/MALT1, t(11;18)

  • Detect genetic markers linked to lymphoma
  • Screen mucosal tissue for cancer signs
  • Assess gastric lymphoma treatment response factors
$3011
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're being evaluated for a possible lymphoma, especially one affecting the stomach, lungs, or other mucosal tissue. It looks for specific genetic changes that help distinguish MALT lymphoma from other low-grade lymphomas. This information can be important for understanding your diagnosis and planning next steps.

What's included in this test?

This test uses a technique called FISH (fluorescence in situ hybridization) to look for a specific gene rearrangement called MALT1, and if found, automatically checks for a related fusion between the BIRC3 (API2) and MALT1 genes. These genetic changes are closely linked to a type of lymphoma that starts in mucosal tissue, so finding them can help clarify a diagnosis. Detecting this fusion is also useful because it's linked to how certain gastric lymphomas respond to treatment.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding means for this specific genetic marker. Because this is a specialized diagnostic test, next steps often include additional genetic testing or clinical follow-up depending on what is found. You can download the standard lab report directly from your account at any time. If you retest in the future, you'll also be able to track results over time using the trends feature.

How can I naturally support my immune system during evaluation?
While no lifestyle change can affect a genetic test result, supporting your overall immune health can be helpful during a diagnostic workup. Eating a balanced diet with plenty of fruits, vegetables, and lean protein, staying hydrated, getting regular sleep, and managing stress can all support your body's general resilience. Avoiding smoking and limiting alcohol are also commonly recommended during any period of medical evaluation.
When will I get my results?
Results for this test are typically ready within about 7 days of your sample being processed at the lab. FISH testing involves specialized lab procedures, which is why it takes a bit longer than routine blood work. You'll be notified as soon as your results are ready to view in your account.
Who should consider this test?
This test is generally considered for people who have findings suggestive of a marginal zone or MALT lymphoma, often after a biopsy of affected tissue such as the stomach or lungs. It's also relevant for people already diagnosed with a lymphoma who need further genetic characterization to guide treatment decisions. This is a specialized test, so it's typically used as part of a broader diagnostic workup rather than as a first step.
What symptoms might lead someone to need this type of testing?
People are often referred for this kind of genetic testing after experiencing persistent stomach discomfort, unexplained weight loss, chronic cough or breathing issues, or swelling in the lymph nodes. These symptoms alone don't point to lymphoma specifically, but when combined with imaging or biopsy findings, this test can help clarify what's going on at the genetic level. If you're having ongoing, unexplained symptoms like these, it's worth discussing testing options with wherever you're receiving care.
What does a positive result for the MALT1 or BIRC3/MALT1 fusion mean?
A positive result means the specific genetic rearrangement was found in the tested tissue, which supports a diagnosis of MALT lymphoma. In gastric cases specifically, this finding has also been linked to a lower chance of the lymphoma resolving with standard H. pylori treatment alone. This kind of result is usually reviewed alongside biopsy findings and imaging to build a complete clinical picture.
What does a negative result mean?
A negative result means this particular gene rearrangement was not detected in the sample tested. This doesn't rule out lymphoma altogether, since MALT lymphomas can involve other genetic changes, such as IGH/MALT1, IGH/BCL10, or IGH/FOXP1 rearrangements, that this specific test doesn't check for. Additional testing may be needed to get a fuller genetic picture if lymphoma is still suspected.
What should I do if my results come back abnormal?
If your result is positive for this genetic rearrangement, it's a good idea to discuss the finding along with your other test results, such as biopsy and imaging, to understand your full diagnostic picture. Because this result can influence treatment decisions, especially for gastric lymphoma, timely follow-up is recommended. Keeping a copy of your lab report handy for any future appointments or additional testing is also a smart step.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Demo results
BIRC3(API2)/MALT1 Fusion Gene (FISH) Negative
Demo results
Negative Positive
Negative

What this means

A negative result means this specific gene fusion was not detected in the tested tissue. This does not rule out MALT lymphoma entirely, since other genetic rearrangements can also cause this condition. Your full results should be considered together with biopsy and imaging findings.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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MALT Lymphoma FISH Test with BIRC3/MALT1 Reflex

  • Detect genetic markers linked to lymphoma
  • Screen mucosal tissue for cancer signs
  • Assess gastric lymphoma treatment response factors
$3011
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.