What's this test for?

This test is ideal if you're being evaluated for a possible lymphoma diagnosis and your case involves a suspicious tissue biopsy, especially from the stomach or lungs. It looks for a specific genetic change (a MALT1 gene rearrangement) that helps identify a type of low-grade lymphoma called MALT lymphoma. This information is often used alongside other pathology findings to understand the nature of the abnormal cells.

What's included in this test?

This test uses a single specialized technique (FISH with a break-apart probe) to look for one specific genetic change rather than a panel of biomarkers. It focuses on rearrangements involving the MALT1 gene, which are found in a meaningful portion of MALT lymphoma cases. Detecting this change can help distinguish MALT lymphoma from other similar-looking low-grade lymphomas.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding for the MALT1 rearrangement means. Because this is a specialized genetic test tied to a lymphoma workup, next steps typically involve reviewing the report alongside other biopsy and pathology findings rather than routine retesting. The standard lab report can be downloaded directly from your account for your records. You can also track this and any related results over time using the trends feature.

Who should consider this test?

This test is generally considered for people who already have a tissue biopsy suspicious for lymphoma, particularly involving the stomach, lungs, or other mucosal tissue. It's most relevant when there's a need to confirm or narrow down a MALT lymphoma diagnosis versus other similar conditions. It is not a general screening test for people without prior suspicious findings.

What symptoms indicate I may need this test?

Symptoms that sometimes lead to this kind of testing include persistent stomach discomfort, unexplained weight loss, chronic indigestion, or a mass found during imaging or endoscopy. Some people are also referred after a diagnosis of chronic H. pylori infection that hasn't fully resolved. Ultimately, this test is ordered based on tissue findings, not symptoms alone, so it usually follows an initial biopsy or imaging result.

When will I get my results?

Results for this test are typically ready within about 7 days of your sample being processed at the lab. Because this is a specialized genetic test, it can take a bit longer than routine bloodwork. You'll be notified as soon as your results are posted to your account.

What is MALT1 gene rearrangement and why does it matter?

MALT1 is a gene that, when rearranged or fused with another gene, is linked to the development of MALT lymphoma, a type of slow-growing lymphoma. Finding this rearrangement helps confirm the diagnosis and can also signal how the lymphoma might behave, since certain rearrangements are linked to resistance to standard treatments like H. pylori eradication therapy. This makes it a useful piece of the diagnostic puzzle, not a standalone answer.

What does a positive result mean?

A positive result means the MALT1 rearrangement was detected in the tissue sample, which supports a diagnosis of MALT lymphoma. This finding is typically considered together with other pathology and clinical information rather than on its own. If your result is positive, it's important to follow up promptly given the context of your biopsy findings.

What does a negative result mean?

A negative result means this particular MALT1 rearrangement was not found in the sample tested. This does not fully rule out MALT lymphoma, since other genetic changes (like IGH/BCL10 or IGH/FOXP1 rearrangements) can also cause this condition and aren't covered by this specific test. Additional testing may be needed to fully characterize the abnormal cells.

What should I do if my results are abnormal?

If your result comes back positive for the MALT1 rearrangement, it's a good idea to bring this report to your next follow-up appointment related to your biopsy findings so it can be considered alongside your other test results. Keep a downloaded copy of your report for your records. If you experience worsening symptoms like severe pain, unexplained bleeding, or rapid weight loss, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

MALT1 FISH Test - MALT Lymphoma Gene Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]