What's this test for?

This test is ideal if you or someone in your care has been diagnosed with, or is being evaluated for, MALT lymphoma, a type of slow-growing lymph tissue cancer. It looks for a specific genetic change called the API2/MALT1 fusion, which can help confirm the type of lymphoma present and guide next steps in care. It's typically used alongside other lab and tissue tests, not as a stand-alone screening tool.

What's included in this test?

This is a single, targeted test rather than a panel, so there's just one result to review: whether the API2/MALT1 gene fusion is present in the tissue sample. This fusion happens when two chromosomes swap material in a way that can drive abnormal cell growth in marginal zone tissue, so detecting it helps distinguish MALT lymphoma from other similar-looking conditions.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a positive or negative finding means for this specific genetic marker. Because this is a specialized diagnostic test tied to a cancer workup, next steps usually involve discussing the finding with your ongoing care team rather than routine retesting or lifestyle changes. You can download a standard lab report from your account at any time, and if you have related tests over time, the trends feature lets you keep a record of your results in one place.

How can I naturally support my immune and digestive health?

While this test itself is diagnostic and not something lifestyle changes can influence, general immune and digestive health can be supported through simple habits like eating a fiber-rich diet, staying hydrated, managing stress, and avoiding unnecessary antibiotic use. If a stomach infection with H. pylori is part of your picture, following any recommended treatment fully is important since untreated infection can affect certain lymphoma outcomes. These habits support overall wellness but do not replace medical treatment for a diagnosed lymphoma.

When will I get my results?

Results for this test are generally available within about 7 days of your sample being processed at the lab. This timeframe reflects the specialized nature of FISH genetic testing, which takes longer than routine bloodwork. You'll be notified as soon as your report is ready to view in your account.

Who should consider this test?

This test is generally considered for people who already have a tissue biopsy showing signs consistent with MALT lymphoma and need more detail on the specific genetic subtype. It's also relevant for people with gastric MALT lymphoma who haven't responded well to standard treatment, since this particular gene fusion is linked to treatment resistance. It is not intended as a general screening test for the public.

What symptoms might lead someone to this type of testing?

People are often referred for MALT lymphoma workup after experiencing persistent stomach discomfort, unexplained weight loss, chronic indigestion, or a lump found in the stomach, lungs, or other lymphatic tissue. Chronic Helicobacter pylori infection that doesn't resolve with treatment can also raise concern. These symptoms alone don't confirm lymphoma, but they're often what prompts imaging or biopsy testing that leads to this genetic test.

What does a positive result mean?

A positive result means the API2/MALT1 gene fusion was found in the tested tissue, which supports a diagnosis of MALT lymphoma and may suggest a lower chance of responding to standard H. pylori eradication treatment alone. This information helps clarify what type of lymphoma is present so the right treatment path can be chosen. A positive finding on its own does not indicate how advanced the condition is.

What does a negative result mean?

A negative result means this specific gene fusion was not detected, but it does not rule out MALT lymphoma entirely, since other genetic changes like IGH/MALT1 or IGH/BCL10 rearrangements can also cause this cancer type. Additional testing is often needed to fully characterize the lymphoma if one genetic marker comes back negative. Your full report will explain how this result fits with any other testing done.

What should I do if my results are abnormal?

If your result comes back positive, it's important to share this information as part of your broader lymphoma workup so treatment decisions can take the genetic subtype into account. Because this fusion is linked to resistance to standard H. pylori treatment in gastric cases, additional or alternative treatment approaches may be considered. Keep a copy of your downloadable report handy for any follow-up testing or consultations.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

MALT Lymphoma FISH Test - API2/MALT1 Gene Fusion

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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