What's this test for?

This test is ideal if you're being evaluated for mantle cell lymphoma or plasma cell myeloma and need more information about your specific disease pattern. It looks for a genetic change called the IGH-CCND1 translocation, which is often linked to these conditions. This test is typically used alongside other clinical findings to help understand disease risk and behavior, not as a first-line screening for the general population.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding means for this specific genetic marker. Because this is a specialized test tied to a known or suspected blood cancer, next steps usually involve using this result alongside your broader clinical picture rather than a simple lifestyle change. The standard lab report can be downloaded directly from your account for your records. You can also track this and any future related results over time using the trends feature.

Who should consider this test?

This test is generally considered by people who have already been diagnosed with, or are being worked up for, mantle cell lymphoma or plasma cell myeloma. It's also useful for people whose care team wants more detail on the genetic features of an existing blood or bone marrow abnormality. It is not typically used as a routine or preventive screening test for people without symptoms or a prior abnormal finding.

What symptoms indicate I may need this test?

Symptoms that often lead to this kind of testing include unexplained swollen lymph nodes, persistent fatigue, unexplained weight loss, night sweats, or bone pain. Some people are referred for this test after an abnormal blood test, bone marrow biopsy, or imaging finding suggestive of a lymphoma or myeloma. If you're experiencing these symptoms, this test is often ordered as part of a broader diagnostic workup rather than by itself.

When will I get my results?

Results for this test are generally ready within about 7 days of your sample being processed. This timeframe reflects the specialized lab technique (FISH) used to detect the specific genetic translocation. You'll be notified as soon as your results are posted to your account so you don't need to check repeatedly.

What is the IGH-CCND1 translocation and why does it matter?

The IGH-CCND1 translocation, also called t(11;14), is a swap of genetic material between chromosomes 11 and 14 that causes cells to make too much of a protein called cyclin D1. This change is found in most cases of mantle cell lymphoma and in a portion of plasma cell myeloma cases. Detecting it helps confirm a diagnosis and gives useful information about how the disease may behave.

What does a positive result mean?

A positive result means the lab found the t(11;14) translocation in the cells that were tested, which supports a diagnosis of mantle cell lymphoma or provides useful risk information in plasma cell myeloma. It does not tell you the full extent or stage of disease on its own. This result is meant to be interpreted together with your other test results, imaging, and biopsy findings.

What does a negative result mean?

A negative result means this specific translocation was not detected in the sample tested. This does not rule out lymphoma or myeloma entirely, since these diseases can involve other genetic changes not covered by this particular test. If your care team still suspects one of these conditions, they may recommend additional or broader genetic testing.

How often should I retest?

This is not a routine test that needs regular repeating like a cholesterol or blood sugar panel. Retesting is generally only considered if a new biopsy or bone marrow sample is taken to reassess disease status, relapse, or response to treatment. Your testing schedule should be guided by your overall diagnostic and monitoring plan rather than a fixed interval.

What should I do if my results are abnormal?

If your result comes back positive for the t(11;14) translocation, the next step is usually to review it alongside your other diagnostic tests, such as biopsy results and imaging, to build a complete picture. Keep a copy of your downloadable lab report for your records, since specialized genetic results like this are often referenced during ongoing care planning. If you're experiencing severe symptoms such as significant pain, difficulty breathing, or sudden swelling, seek medical care right away.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

t(11;14) FISH Test - Lymphoma & Myeloma Marker

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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