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FISH lymphoma panel testing for MYC, BCL2, BCL6 gene changes in cancer diagnosis

FISH High-Grade Lymphoma Gene Rearrangement Panel

FISH, High-Grade Lymphoma Panel

  • Classify aggressive high-grade lymphoma subtypes accurately
  • Detect double-hit and triple-hit gene changes
  • Assess treatment planning with genetic detail
$5971
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're already being evaluated for high-grade B-cell lymphoma and your care team needs more detailed information to classify the disease. It's typically used after a biopsy shows lymphoma cells that don't fit neatly into a standard category, or when there's concern about an aggressive "double-hit" or "triple-hit" lymphoma. The results help clarify the exact type of lymphoma so the right treatment approach can be chosen.

What's included in this test?

This panel uses a lab technique called FISH (fluorescence in situ hybridization) to look for specific gene rearrangements inside lymphoma cells that are linked to aggressive, hard-to-classify lymphomas. Checking multiple genes together helps distinguish between different lymphoma subtypes and flags cases where more than one high-risk gene change is present, which can change how aggressive the disease is and how it should be treated.

What happens after I get my results?

Your results will appear in your account along with an explanation of what each finding means for the genes tested. Because this is a specialized cancer classification test, the report will indicate whether specific gene rearrangements were detected, which is information used alongside your other test results for classification purposes. You can download the full lab report from your account at any time, and if repeat testing is ever needed, you can track results over time using the trends feature. If any result suggests an aggressive or urgent finding, seek medical care right away to discuss next steps.

How can I naturally support my immune system during lymphoma evaluation?
While no natural remedy can treat or replace lymphoma testing and treatment, some everyday habits support your overall immune health during this process. Eating a balanced diet rich in fruits, vegetables, and lean protein, staying well hydrated, getting consistent sleep, and avoiding smoking or excess alcohol can help your body cope better overall. These steps are supportive only and should never delay or replace urgent medical evaluation for lymphoma.
When will I get my results?
Results for this specialized FISH panel typically take about 7 days to process, since the lab has to analyze the genetic material inside the cells for each of the specific gene rearrangements. You'll receive a notification as soon as your results are ready in your account. Because this test involves detailed cell analysis, it takes longer than routine blood work, so plan for about a week's turnaround.
Who should consider this test?
This test is generally considered for people who already have a lymphoma diagnosis or a biopsy showing atypical or ambiguous features that need further classification. It's most relevant when there's concern about aggressive subtypes like Burkitt lymphoma or high-grade B-cell lymphoma with unusual features. It is not a general screening test for people without a prior indication of lymphoma.
What symptoms might indicate I need this kind of lymphoma testing?
Symptoms that often lead to lymphoma evaluation include swollen lymph nodes that don't go away, unexplained weight loss, persistent fevers, drenching night sweats, and ongoing fatigue. If you're experiencing these symptoms, the first step is usually imaging and a biopsy, and this FISH panel may be ordered afterward to help classify what's found. Seek medical care promptly if you notice a rapidly growing lump or severe symptoms.
What is a 'double-hit' or 'triple-hit' lymphoma and why does it matter?
A 'double-hit' lymphoma has changes in two of the genes tested here (commonly MYC plus BCL2 or BCL6), while a 'triple-hit' lymphoma has changes in all three. These terms matter because lymphomas with these combined gene changes tend to behave more aggressively and often need more intensive treatment approaches than typical lymphomas. Identifying this pattern early helps guide which treatment path is most appropriate.
What does a positive MYC gene rearrangement result mean?
A positive result means the MYC gene has been rearranged in a way that's associated with more aggressive lymphoma behavior. On its own, it doesn't determine treatment, but combined with the BCL2 and BCL6 results, it helps classify the lymphoma subtype. This finding should be discussed with your care team as soon as possible so it can be factored into the treatment plan.
What should I do if my results show a gene rearrangement?
If your results show one or more of the gene rearrangements tested, it's important to seek medical care promptly so the finding can be incorporated into your overall diagnosis and treatment planning. Bring your downloadable lab report to that discussion since it lays out exactly which genes were affected. This is time-sensitive information, so don't wait to follow up on an abnormal result.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
MYC (8q24) Gene Rearrangement Negative
Demo results
Negative (Not Detected) Positive (Detected)
Negative

What this means

A negative result means no MYC gene rearrangement was detected in the sample tested. This makes a 'double-hit' or 'triple-hit' high-grade lymphoma less likely, though the overall diagnosis still depends on the BCL2 and BCL6 results and other biopsy findings. Results should always be interpreted together with your full pathology report.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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FISH High-Grade Lymphoma Gene Rearrangement Panel

  • Classify aggressive high-grade lymphoma subtypes accurately
  • Detect double-hit and triple-hit gene changes
  • Assess treatment planning with genetic detail
$5971
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.