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HER2/neu FISH test for breast cancer patients assessing targeted therapy eligibility

HER2/neu FISH Test for Breast Cancer Treatment Planning

FISH, HER-2/neu with Reflex to IHC

  • Assess breast cancer treatment eligibility options
  • Detect HER2 gene amplification status
  • Guide targeted therapy treatment decisions
$2273
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you've been diagnosed with breast cancer and need to find out whether HER2-targeted therapy could work for you. It looks closely at your tumor tissue to see if the HER2 gene is making too many copies of itself, which affects how the cancer grows and which treatments are likely to help. This information is a key part of building a treatment plan after a breast cancer diagnosis.

What's included in this test?

This test uses a technique called FISH to look directly at the HER2 gene inside your tumor cells and count how many copies are present. If the FISH result is inconclusive, the same tissue sample is automatically checked with a second method (IHC) that measures the HER2 protein on the cell surface. Together these two approaches give a more complete and reliable picture of your tumor's HER2 status.

What happens after I get my results?

Your results will show up in your account along with an explanation of what the HER2 finding means for your specific report. If the initial FISH result comes back unclear, the lab automatically runs a follow-up IHC test on the same sample so you get a definitive answer without needing a new specimen. You can download the full lab report from your account at any time, and because this is typically a one-time diagnostic test tied to a specific tumor sample, retesting is usually only needed if a new biopsy is taken. If your results raise questions about next steps, treatment planning should happen promptly given the nature of a cancer diagnosis.

How can I naturally support treatment outcomes during breast cancer care?
While no lifestyle change can substitute for appropriate cancer treatment, staying active, eating a balanced diet rich in fruits and vegetables, and getting enough sleep can help your body handle treatment better. Reducing alcohol intake and avoiding smoking are also linked to better outcomes in breast cancer patients. Managing stress through gentle activities like walking, meditation, or support groups can also make a meaningful difference during this time.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. If your case requires the additional IHC reflex test due to an inconclusive FISH result, it may take a little longer since that second test is run on the same tissue sample. You'll be notified as soon as your full report is available in your account.
Who should consider this test?
Anyone recently diagnosed with breast cancer should consider this test, since HER2 status is a standard part of understanding a new breast cancer diagnosis. It's especially relevant if a treatment plan involving HER2-targeted therapy is being considered. Because HER2 status affects treatment options, testing is recommended for essentially all newly diagnosed invasive breast cancer cases.
What does a positive (amplified) HER2 result mean?
A positive or amplified result means your tumor cells have extra copies of the HER2 gene, causing them to produce more HER2 protein than normal. This type of cancer, sometimes called HER2-positive, tends to grow faster than HER2-negative cancers but often responds well to HER2-targeted therapies. Knowing this status helps guide which treatments are likely to be most effective for your specific cancer.
What does a negative (non-amplified) HER2 result mean?
A negative result means your tumor does not have extra copies of the HER2 gene, so it's classified as HER2-negative. This means HER2-targeted therapies are not expected to be effective, and other treatment approaches will be more appropriate. Your full report will explain exactly where your result falls and what it means for treatment planning.
What causes HER2 gene amplification in breast cancer?
HER2 amplification happens due to a genetic change within the tumor cells themselves, not something caused by diet, lifestyle, or environment. It occurs in up to 20% of primary breast cancers and is a random mutation that happens as cells divide and grow abnormally. It's not something you did or could have prevented, and it's not passed down through families in most cases.
What should I do if my results show HER2 amplification?
If your results show HER2 amplification, the next step is typically discussing HER2-targeted therapy options as part of your overall treatment plan. It also helps to talk through the full lab report so you understand exactly what your numbers mean. Keeping a copy of your results and tracking any future related testing over time can help keep your care organized.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
HER2/neu Gene Amplification (FISH) Negative (Not Amplified)
Demo results
Negative (Not Amplified) Positive (Amplified)
Negative (Not Amplified)

What this means

A negative result means your tumor cells do not show extra copies of the HER2 gene. This means your cancer is classified as HER2-negative, so HER2-targeted therapies are not expected to help, and other treatment approaches will be more suitable.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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HER2/neu FISH Test for Breast Cancer Treatment Planning

  • Assess breast cancer treatment eligibility options
  • Detect HER2 gene amplification status
  • Guide targeted therapy treatment decisions
$2273
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.