What's this test for?

This test is ideal if you're being evaluated for Ewing sarcoma or a related bone or soft tissue tumor and need genetic confirmation of the diagnosis. It looks for a specific rearrangement in the EWSR1 gene that is strongly associated with Ewing sarcoma and PNET (primitive neuroectodermal tumor). It's typically used alongside imaging and tissue biopsy findings to confirm what type of tumor is present.

What's included in this test?

This test uses a specialized FISH (fluorescence in situ hybridization) technique with a dual-color break-apart probe to examine a single, specific location on your chromosomes. It checks for a break or rearrangement in the EWSR1 gene, which is the genetic hallmark found in the majority of Ewing sarcoma and PNET tumors. Because it targets this one genetic change directly, it provides a very specific answer rather than a broad panel of markers.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding means for the EWSR1 gene region. If a rearrangement is detected, the next step is usually additional testing and treatment planning based on the confirmed diagnosis, and this should be addressed promptly given the nature of this condition. You can download a standard lab report directly from your account for your records, and if repeat testing is ever needed, you can track results over time using the trends feature.

How can I naturally support recovery during cancer evaluation?

While no natural remedy replaces proper cancer diagnosis and treatment, supporting your body with balanced nutrition, adequate protein, and good sleep can help you feel stronger during this process. Gentle physical activity, when your care allows it, can help manage stress and fatigue. Avoiding smoking and excess alcohol also supports your body's ability to handle any upcoming treatment.

When will I get my results?

Results for this specialized genetic test are typically ready within about 7 days after your sample is processed at the lab. FISH testing requires careful lab work to visualize the chromosome rearrangement clearly, which is why it takes a bit longer than routine blood tests. You'll be notified as soon as your results are posted to your account.

Who should consider this test?

This test is typically considered for individuals who have a tumor biopsy suggestive of Ewing sarcoma or PNET on imaging or initial pathology review. It's also useful when doctors reviewing a biopsy need extra genetic confirmation before finalizing a treatment plan. It is not a general screening test for the public but rather a targeted diagnostic tool for a specific suspected condition.

What symptoms might lead someone to need this test?

Symptoms that often lead to this type of testing include persistent, unexplained bone pain, a growing lump or mass in bone or soft tissue, swelling, or fatigue that doesn't go away. These symptoms are often first investigated with imaging like an X-ray or MRI, and if a tumor is found, a biopsy sample may then be sent for this genetic test. It's most often ordered as a follow-up to those initial findings rather than as a first step.

What does a positive EWSR1 rearrangement result mean?

A positive result means the lab found a break or rearrangement in the EWSR1 gene in your tissue sample, which strongly supports a diagnosis of Ewing sarcoma or PNET. This finding helps confirm the type of tumor so that an appropriate treatment approach can be chosen. Because this is a serious finding, prompt follow-up and treatment planning are important next steps.

What does a negative result mean?

A negative result means no EWSR1 gene rearrangement was detected in the sample tested, which makes Ewing sarcoma or PNET less likely as the diagnosis. However, a small number of Ewing-related tumors involve different genetic changes not captured by this specific probe, so other tests may still be needed to fully rule out the condition. Your results report will explain the finding in the context of this specific probe.

What should I do if my results are abnormal?

If your result shows a rearrangement, treat this as time-sensitive and move forward quickly with next steps such as further staging, imaging, or treatment planning. Bring your downloadable lab report to any follow-up appointments so the full technical detail of the finding is available. Because Ewing sarcoma can progress, don't delay in acting on a positive result.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

EWSR1 FISH Test - Ewing Sarcoma Gene Confirmation

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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