What's this test for?

This test is ideal if you or a loved one has been diagnosed with acute lymphoblastic leukemia (ALL) and needs more information about the specific genetic changes driving the disease. It helps identify the ETV6/RUNX1 (TEL/AML1) gene fusion, which is linked to a more favorable treatment response, especially in children. It's also used to monitor for signs that the leukemia may be coming back after treatment.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding means for this specific gene fusion. Depending on the result, next steps may include continuing your current treatment plan, scheduling follow-up testing to monitor for recurrence, or seeking care promptly if new symptoms appear. A standard lab report is available to download directly from your account, and you can track results over time using the trends feature if you retest in the future.

Who should consider this test?

This test is most relevant for individuals recently diagnosed with B-lineage acute lymphoblastic leukemia, particularly children, since this fusion gene shows up in about 1 in 4 pediatric ALL cases. It's also useful for anyone in active leukemia treatment who needs ongoing monitoring for relapse. Adults with ALL may also be tested, though this fusion is less common in that age group.

What symptoms indicate I may need this test?

Symptoms like unexplained fatigue, frequent infections, easy bruising or bleeding, bone pain, and swollen lymph nodes can be signs of leukemia that warrant genetic testing once a diagnosis is suspected or confirmed. If you've already been diagnosed with ALL, this test isn't about new symptoms but about better understanding the biology of the existing diagnosis. Persistent or returning symptoms after treatment can also be a reason to test for recurrence.

What is the ETV6/RUNX1 fusion gene and why does it matter?

The ETV6/RUNX1 fusion gene forms when two chromosomes (12 and 21) swap pieces in a process called translocation, creating an abnormal gene that can drive leukemia. It matters because its presence is linked to a better response to chemotherapy and generally a more favorable outlook, especially in children with ALL. Knowing whether this fusion is present helps put your specific diagnosis into context.

When will I get my results?

Results for this specialized FISH test typically take about 7 days to process. This timeframe reflects the detailed lab work needed to detect the specific chromosome rearrangement being tested for. You'll be notified as soon as your results are ready to view in your account.

What does a positive result mean?

A positive result means the ETV6/RUNX1 fusion gene was detected, which is generally associated with a more favorable prognosis and better response to standard chemotherapy in ALL, particularly in pediatric patients. It does not predict the outcome on its own but adds helpful context to the overall diagnosis. This information is often used alongside other clinical findings to understand your specific case.

What does a negative result mean?

A negative result means this particular gene fusion was not detected, which simply means this specific genetic marker isn't part of your leukemia's profile. It doesn't rule out ALL or other genetic changes that may be present, since leukemia can involve many different genetic abnormalities. Other tests are often used together with this one to build a full picture.

How often should I retest?

Retesting frequency depends on your treatment stage and is often used to monitor for recurrence after initial treatment ends. Many people retest at intervals recommended during active monitoring periods, such as every few months, tapering off as time passes without relapse. Using the trends feature in your account can help you and your care team track any changes over time.

What should I do if my results are concerning?

If your result shows the presence of this fusion gene or any unexpected finding, it's important to seek medical care promptly to discuss what it means for your treatment plan. Keep a copy of your downloadable lab report handy, as it can help guide follow-up conversations about next steps. If you experience severe symptoms like high fever, uncontrolled bleeding, or extreme fatigue, seek emergency medical care right away.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

ETV6/RUNX1 FISH Test - Leukemia Prognosis & Monitoring

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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