What's this test for?

This test is ideal if you're being evaluated for a suspected blood cancer called acute promyelocytic leukemia, or APL. It looks for a specific genetic change in blood or bone marrow cells that helps confirm this diagnosis quickly, which matters because APL can progress fast and needs urgent attention. This test is typically ordered when other blood findings or symptoms already point toward a possible leukemia.

What's included in this test?

This test uses a specialized genetic technique called FISH to look for a swap of material between two chromosomes that creates an abnormal fusion gene. Detecting this fusion gene matters because it is found in the vast majority of people with acute promyelocytic leukemia and helps confirm this specific diagnosis so the right treatment path can be identified quickly.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding means for this specific genetic marker. If the translocation is detected, this is a significant finding and you should seek medical care right away, since APL requires urgent evaluation and treatment. The standard lab report can be downloaded from your account at any time, and if you need repeat testing later to track treatment response, you can compare results over time using the trends feature.

How can I naturally support healthy blood cell production?

While this genetic test result can't be changed by lifestyle habits, supporting your overall blood and immune health with a nutrient-rich diet, adequate sleep, and avoiding known toxins like tobacco smoke and excess alcohol is generally helpful. Eating iron-rich and folate-rich foods, such as leafy greens and lean proteins, supports normal blood cell formation. These steps do not treat leukemia but can support your general well-being while you pursue appropriate care.

When will I get my results?

Results for this specialized genetic test are typically ready within about 7 days after your sample is processed at the lab. Because this test is often used when a leukemia diagnosis is suspected, turnaround time is prioritized to support timely next steps. You'll be notified as soon as your results are posted to your account.

Who should consider this test?

This test is generally considered when a blood count or bone marrow exam has already raised suspicion of acute promyelocytic leukemia. It's also useful for people with symptoms like unusual bruising, bleeding, fatigue, or abnormal blood cell counts that suggest a possible blood cancer. It is not a routine screening test for the general population.

What symptoms indicate I may need this test?

Symptoms that may point toward needing this test include unexplained bruising or bleeding, small red or purple spots on the skin, severe fatigue, frequent infections, or abnormal results on a routine blood count. These symptoms can have many causes, but when combined with concerning blood work, this test helps clarify whether a specific leukemia-related genetic change is present. If you have severe bleeding or extreme fatigue, seek medical care promptly.

What does a positive result mean?

A positive result means the specific genetic fusion linked to acute promyelocytic leukemia was detected in your sample. This is considered a significant, actionable finding and typically means urgent follow-up care is needed, since APL can progress quickly but is highly treatable when caught early. Because this test doesn't check for related genetic variants, additional testing may be recommended to fully characterize the finding.

What does a negative result mean?

A negative result means this specific fusion gene was not detected in your sample. This makes the specific form of leukemia associated with this genetic change less likely, though it doesn't rule out other types of leukemia or other genetic variants of APL that involve different chromosome partners. Your results report explains this distinction in plain terms.

What should I do if my results are abnormal?

If your result is positive, treat this as an urgent finding and seek medical care as soon as possible, since timely treatment for this condition significantly improves outcomes. Bring a copy of your downloadable lab report with you to any follow-up visit. Avoid delaying care while waiting on additional confirmatory testing.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

APL FISH Test - PML/RARA Leukemia Gene Detection

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]