What's this test for?

This test is ideal if you're being evaluated for alveolar rhabdomyosarcoma (ARMS), a rare soft tissue cancer that most often appears in people between 10 and 25 years old. It's typically used alongside imaging and tissue biopsy when a soft tissue mass has already been found and more specific information is needed to confirm the type of tumor. This test helps distinguish ARMS from other similar-looking tumors by looking for a specific gene change linked to this cancer.

What's included in this test?

This test looks specifically for rearrangements involving the FOXO1 (FKHR) gene on chromosome 13. This gene change matters because it's found in most cases of alveolar rhabdomyosarcoma and helps separate this cancer type from other similar tumors, which affects how the condition is understood and tracked. Detecting this rearrangement also provides prognostic information, since specific fusion patterns are linked to different expected disease courses.

What happens after I get my results?

Your results will be available in your account, with an explanation of what the finding means and how it compares to a normal (negative) result. Because this is a specialized cancer marker test, next steps usually involve sharing the report as part of a broader diagnostic workup rather than routine retesting. The standard lab report can be downloaded directly from your account for your records. If you're tracking multiple related tests over time, you can also view them together using the trends feature in your account.

How can I naturally support healthy cell growth and immune function?

While no lifestyle change can replace proper cancer testing and treatment, general habits like eating a nutrient-rich diet, getting regular sleep, staying physically active as tolerated, and avoiding tobacco and excess alcohol support overall immune health. Reducing stress through activities like light exercise, stretching, or mindfulness may also help your body cope during a diagnostic period. These steps are supportive only and are not a substitute for appropriate cancer screening or treatment. Always prioritize any urgent symptoms by seeking immediate medical care.

When will I get my results?

Results for this specialized genetic test are typically ready within about 7 days after your sample is processed at the lab. Because this test involves detailed genetic analysis, it takes longer than routine bloodwork. You'll be notified as soon as your results are ready to view in your secure account.

Who should consider this test?

This test is generally considered for people who already have a soft tissue mass or tumor identified through imaging or biopsy, particularly children, teens, and young adults, since ARMS most commonly occurs between ages 10 and 25. It's a specialized follow-up test rather than a general screening tool. It's most relevant when there's a need to confirm tumor type and gather information about expected disease behavior.

What symptoms indicate I may need this test?

Signs that may lead to this type of testing include a noticeable lump or swelling in the muscle or soft tissue, unexplained pain in that area, or a mass found during imaging done for other reasons. In some cases, symptoms depend on the tumor's location, such as vision changes with tumors near the eye or urinary symptoms with tumors near the bladder. Because these symptoms can have many causes, this genetic test is used only after initial findings suggest a possible rhabdomyosarcoma.

What is FOXO1 gene rearrangement and why does it matter?

FOXO1 is a gene that normally helps control how cells grow and mature. In alveolar rhabdomyosarcoma, this gene can become rearranged and fused with another gene (most often PAX3 or PAX7), creating an abnormal signal that drives the cancer's growth. Identifying this rearrangement helps confirm the diagnosis and gives information about how the cancer may behave over time.

What does a positive result for FOXO1 rearrangement mean?

A positive result means the FOXO1 gene rearrangement was detected, which supports a diagnosis of alveolar rhabdomyosarcoma rather than other similar tumor types. Patients with this rearrangement, especially the PAX3/FOXO1 fusion, tend to have a more aggressive disease course compared to those without it. This finding is usually one part of a larger diagnostic picture that includes imaging, biopsy, and other lab work.

What should I do if my results show a gene rearrangement?

If your report shows a detected FOXO1 rearrangement, the next step is usually further testing to identify the exact fusion type (PAX3/FOXO1 or PAX7/FOXO1), since this affects prognosis and treatment planning. It's important to move quickly to a full diagnostic and treatment plan given the nature of this condition. Keep your downloaded report and any prior imaging or biopsy results together, as they'll all be needed for a complete picture. If you experience worsening symptoms such as increasing pain or swelling, seek medical care right away.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Alveolar Rhabdomyosarcoma Gene Test - FOXO1 Rearrangement

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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