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FISH ALK gene rearrangement test for lung cancer patients considering targeted therapy

ALK Gene Rearrangement Test for Lung Cancer Treatment

FISH, ALK 2p23 Rearrangement, Lung Cancer (NSCLC)

  • Detect ALK gene tumor changes
  • Guide targeted lung cancer treatment
  • Assess eligibility for crizotinib therapy
$2890
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you've been diagnosed with non-small cell lung cancer and need to know whether your tumor has a specific gene change called an ALK rearrangement. Knowing this helps determine if targeted therapies like crizotinib (Xalkori) could work for your specific cancer. It's typically used after a lung cancer diagnosis to guide treatment decisions, not as a general screening test.

What's included in this test?

This test looks specifically for a rearrangement of the ALK gene in lung tumor tissue using a specialized technique called FISH (fluorescence in situ hybridization). This single, focused analysis matters because ALK gene rearrangements identify a subset of non-small cell lung cancer patients who may respond well to targeted drug therapies instead of, or alongside, traditional chemotherapy.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative ALK rearrangement result means for your tissue sample. Because this is a qualitative tissue test tied to cancer treatment planning, next steps typically involve using this result alongside your broader treatment plan rather than lifestyle changes or retesting on a schedule. The standard lab report is downloadable directly from your account for your records. If results are unclear or you have concerning symptoms, seek medical care promptly.

How can I naturally support lung health during cancer treatment?
While no natural remedy replaces cancer treatment, general lifestyle steps can support your body during this time. Eating a balanced diet rich in fruits, vegetables, and lean protein helps maintain strength and immune function. Avoiding smoking and secondhand smoke, staying physically active as tolerated, and managing stress through rest and light activity can also support overall wellbeing during treatment.
When will I get my results?
Results for this test are typically ready within about 7 days of your sample being processed at the lab. This timeframe reflects the specialized FISH technique used to examine the tumor tissue closely. You'll be notified as soon as your results are ready to view in your account.
Who should consider this test?
This test is most relevant for people already diagnosed with non-small cell lung cancer who are exploring treatment options. It's especially useful if you and your treatment team are considering targeted therapies rather than standard chemotherapy alone. It is not intended as a general cancer screening test for people without a diagnosis.
What symptoms indicate I may need this test?
This test isn't based on symptoms directly — it's used after a lung cancer diagnosis has already been made through imaging and biopsy. Symptoms that typically lead to that initial lung cancer diagnosis include a persistent cough, unexplained weight loss, chest pain, coughing up blood, or shortness of breath. If you're experiencing these symptoms without a diagnosis yet, seek medical evaluation first.
What is an ALK gene rearrangement and why does it matter?
An ALK gene rearrangement happens when the ALK gene gets rearranged or fused with another gene, causing cells to grow and divide abnormally. In some non-small cell lung cancers, this rearrangement drives tumor growth. Identifying it matters because certain targeted drugs are designed specifically to block the abnormal signal created by this rearrangement, potentially working better than standard chemotherapy for these tumors.
What does a positive ALK result mean?
A positive result means your tumor tissue shows the ALK gene rearrangement, which suggests your cancer may respond to targeted ALK-inhibitor therapies like crizotinib. This is generally seen as helpful information because it opens up additional treatment options beyond standard chemotherapy. Your full report will explain the specific pattern detected in your sample.
What should I do if my results show an ALK rearrangement?
If your results are positive for an ALK rearrangement, this information is meant to be used alongside your cancer treatment planning to discuss whether targeted therapy options are appropriate for you. Keep a copy of your downloadable report handy since treatment decisions often reference these results. If you experience worsening symptoms at any point, seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
ALK Gene Rearrangement (FISH) Positive
Demo results
Negative Positive
Positive

What this means

A positive result means your tumor cells show a rearrangement in the ALK gene, which can drive cancer growth in some non-small cell lung cancers. This finding suggests your cancer may respond to targeted ALK-inhibitor therapies rather than, or in addition to, standard chemotherapy. A negative result means no ALK rearrangement was detected in the sample tested.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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ALK Gene Rearrangement Test for Lung Cancer Treatment

  • Detect ALK gene tumor changes
  • Guide targeted lung cancer treatment
  • Assess eligibility for crizotinib therapy
$2890
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.