What's this test for?

This test is ideal if you're already diagnosed with, or being worked up for, a high-risk form of acute lymphoblastic leukemia (ALL) and need more detail on the genetic drivers behind it. It looks for a specific gene rearrangement (ABL2) that is linked to a hard-to-treat subtype called Ph-like or BCR-ABL1-like ALL. Knowing whether this fusion is present can help guide whether targeted drug therapy is a treatment option worth exploring.

What's included in this test?

This is a single, focused genetic test rather than a multi-marker panel, so there isn't a list of separate biomarkers to explain. Instead, it uses a lab technique called FISH (fluorescence in situ hybridization) to look specifically for a rearrangement involving the ABL2 gene, which is one of several genes known to drive Ph-like ALL when fused with a partner gene. Identifying this single genetic change matters because it directly affects which treatments, including targeted kinase inhibitor drugs, are likely to work.

What happens after I get my results?

Your results will show up securely in your account, with an explanation of what a positive or negative finding means for this specific gene rearrangement. If the ABL2 fusion is detected, the next step is usually discussing targeted tyrosine kinase inhibitor therapy options based on this finding, and if it's not detected, other genetic drivers may need to be explored. A full standard lab report is available to download directly from your account at any time. You can also track this and any related results over time using the trends feature in your account.

How can I naturally support my immune and blood health?

While no lifestyle change can replace targeted leukemia therapy, supporting your body during treatment can still help you feel better day to day. Eating a nutrient-dense diet, staying well hydrated, and prioritizing rest can support your energy levels and immune function during intensive treatment periods. Gentle movement, when your care team clears it, and stress-reduction practices like breathing exercises can also help you cope with the physical and emotional demands of treatment. Always pair these habits with the treatment plan tied to your test results.

When will I get my results?

This test typically takes about 7 days from the time your sample is collected to when results are ready. Because this is a specialized genetic test, it takes longer to process than routine bloodwork, so plan accordingly if you're coordinating next treatment steps. You'll be notified as soon as your results are posted to your secure account.

Who should consider this test?

This test is meant for people who already have a diagnosis of, or strong suspicion of, high-risk B-cell acute lymphoblastic leukemia and need more information about the underlying genetic drivers. It's especially relevant if initial testing suggests a Ph-like or BCR-ABL1-like pattern, since ABL2 fusions are one of several possible causes. It is not a general screening test for the public and is typically ordered as part of a broader leukemia workup.

What symptoms indicate I may need this test?

On its own, ABL2 fusion testing isn't triggered by everyday symptoms — it's ordered after someone shows signs of leukemia, such as unexplained fatigue, frequent infections, easy bruising or bleeding, bone pain, or swollen lymph nodes, and initial blood work points toward ALL. If you or someone you know has already been told bloodwork looks concerning for leukemia, this type of genetic testing is often a logical next step. It should always follow, not replace, initial diagnostic blood counts and bone marrow evaluation.

What is Ph-like ALL and why does it matter?

Ph-like ALL (also called BCR-ABL1-like ALL) is a subtype of leukemia that behaves genetically similar to classic Philadelphia-chromosome-positive leukemia, even though the Philadelphia chromosome itself isn't present. It tends to be more aggressive and harder to treat with standard chemotherapy alone. Identifying it matters because patients with this subtype often respond better when targeted kinase inhibitor drugs are added to their treatment plan.

What does a positive ABL2 fusion result mean?

A positive result means the lab found a rearrangement involving the ABL2 gene, which places the leukemia into the Ph-like or BCR-ABL1-like category. This information is used to decide if targeted tyrosine kinase inhibitor therapy could be added to the treatment plan, since these drugs are designed to block the abnormal signaling caused by this type of fusion. This result does not change the original leukemia diagnosis; it adds more precise genetic detail to guide treatment choices.

How often should I retest?

This test is generally done once at diagnosis, or at relapse, to characterize the genetic profile of the leukemia rather than as a routine repeat test. Retesting may be considered if the leukemia relapses or if treatment isn't responding as expected, since the genetic picture can occasionally change. Your treatment team's monitoring plan, not a fixed schedule, should guide whether or when this test is repeated.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

FISH ABL2 Test - Ph-like Leukemia Gene Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]