What's this test for?

This test is ideal if you're already being evaluated for a high-risk form of acute lymphoblastic leukemia (ALL) and need more information about the genetic changes driving it. It looks for ABL1 gene rearrangements that are linked to a subtype called Ph-like or BCR-ABL1-like ALL, which behaves aggressively and responds to specific targeted drugs. This test is typically used alongside other leukemia workup, not as a general screening tool for the public.

What's included in this test?

This test uses a technique called FISH (fluorescence in situ hybridization) to look specifically at the ABL1 gene for rearrangements or fusions. These particular changes matter because they identify a high-risk leukemia subtype that shares genetic features with Philadelphia chromosome-positive leukemia, and finding them opens the door to treatment with targeted kinase inhibitor medications instead of relying on standard chemotherapy alone.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a positive or negative finding means for this specific gene change. Because this is a specialized diagnostic test tied to an active leukemia workup, next steps usually involve sharing the report with your treatment team so it can guide therapy decisions, including whether targeted kinase inhibitor drugs may be an option. You can download a standard lab report directly from your account at any time, and if repeat testing is needed later to track treatment response, you can compare results over time using the trends feature.

How can I naturally support my immune system during treatment?

While no natural remedy replaces targeted leukemia treatment, simple habits can support your body during this process. Eating a balanced diet with adequate protein, staying well hydrated, getting consistent rest, and avoiding infections through good hygiene can help your immune system function better. Gentle movement, when your care plan allows it, can also help maintain energy and mood during treatment.

When will I get my results?

Results for this specialized FISH test typically take about 7 days to process. This timeframe reflects the detailed lab work involved in analyzing chromosome and gene rearrangements under a microscope, which takes longer than routine blood work. You'll be notified as soon as your results are ready in your account.

Who should consider this test?

This test is generally considered for individuals already diagnosed with or strongly suspected of having high-risk acute lymphoblastic leukemia, particularly when a Ph-like or BCR-ABL1-like subtype is suspected. It's most relevant when treatment teams are trying to determine if targeted kinase inhibitor therapy could be part of the treatment plan. It is not intended as a general wellness or screening test for people without a leukemia diagnosis.

What symptoms might lead to needing this type of test?

Symptoms that often lead to a leukemia workup include unexplained fatigue, easy bruising or bleeding, frequent infections, bone or joint pain, and swollen lymph nodes. If blood work already shows abnormal white blood cell counts or blast cells, more specific genetic tests like this one are often ordered to characterize the leukemia subtype. These symptoms alone don't confirm leukemia, but they're common reasons this kind of specialized testing gets ordered.

What is ABL1 and why does it matter?

ABL1 is a gene that normally helps control cell growth and division. When ABL1 fuses abnormally with other genes, it can create a faulty signal that tells cells to grow uncontrollably, which is a key driver in certain high-risk leukemias. Identifying this fusion matters because it points to specific targeted therapies, called tyrosine kinase inhibitors, that can directly block this abnormal signal.

What does a positive ABL1 rearrangement result mean?

A positive result means the lab found an abnormal fusion involving the ABL1 gene, which is associated with a high-risk, Ph-like leukemia subtype. This finding usually means the leukemia has active kinase signaling that may respond well to targeted kinase inhibitor drugs rather than standard chemotherapy alone. This result is typically used to help shape a more personalized treatment approach.

How often should this test be repeated?

This test is usually done once at diagnosis to identify the genetic subtype of leukemia, rather than on a recurring schedule like routine wellness panels. Your treatment team may recommend related follow-up testing later to monitor how the leukemia responds to treatment, but that typically involves different tests rather than repeating this same FISH panel. Check your order confirmation or treatment plan for any specific retesting guidance.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

FISH ABL1 Test - High-Risk Leukemia Gene Analysis

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]