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First trimester prenatal screening test for expecting mothers checking Down Syndrome risk

First Trimester Screen — Down Syndrome Risk Test

First Trimester Screen, hCG

  • Screen for early pregnancy chromosomal risk
  • Check baby's Down Syndrome risk early
  • Assess Trisomy 18 risk factors
$493
LegitScript certified merchant
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're pregnant and between 10 and 13.9 weeks along, and you want early information about your baby's risk for Down Syndrome and Trisomy 18. It's a routine part of prenatal care for many expecting parents who want to plan ahead or simply gain peace of mind. This screening does not diagnose a condition, but it helps identify if further testing might be useful.

What's included in this test?

This screen looks at hCG, a hormone produced during pregnancy, along with other markers used together to estimate risk. Measuring hCG levels helps assess how your pregnancy is progressing, since unusual levels can be associated with a higher chance of certain chromosomal conditions. The combination of markers gives a more accurate risk estimate than any single value alone.

What happens after I get my results?

Your results will be available in your account, with the normal reference range explained next to your value so you understand what it means. Depending on your result, next steps may include additional screening or diagnostic testing, or simply continuing routine prenatal monitoring if your risk score falls in the expected range. A standard lab report is available to download from your account at any time. You can also use the trends feature to keep a record of this and other results over the course of your pregnancy.

How can I naturally support a healthy pregnancy?
While you can't change your baby's genetic risk factors, you can support a healthy pregnancy overall by eating a balanced diet rich in folate, staying well hydrated, getting regular light exercise if approved, and avoiding alcohol, smoking, and unnecessary medications. Taking a prenatal vitamin with folic acid is one of the most well-supported steps for a healthy pregnancy. Getting enough sleep and managing stress also support your overall well-being during this time.
When will I get my results?
Results are typically ready within about 7 days of your blood draw. Because timing matters for this screening (it's only accurate between 10.0 and 13.9 weeks gestation), it's best to schedule your blood draw as early as possible within that window so you have time to consider next steps if needed.
Who should consider this test?
This test is a good fit for anyone in early pregnancy, between 10 and 13.9 weeks, who wants early insight into chromosomal risk for their baby. It's especially useful for those who want information as early as possible in pregnancy, since first trimester screening happens earlier than many other prenatal screening options. It's a personal choice, and many people choose it simply for added information and peace of mind.
What symptoms indicate I may need this test?
This isn't a symptom-based test — there typically aren't symptoms that signal a chromosomal risk, which is exactly why screening exists. Instead, the main factor is timing: being pregnant and within the 10.0-13.9 week gestation window is what makes this test relevant. Age, family history, or personal preference for early information are common reasons people choose to screen.
What does a higher risk result mean?
A higher risk result means the combination of your markers and other factors suggests an increased chance of Down Syndrome or Trisomy 18, but it does not mean your baby definitely has either condition. Many people with a higher risk score go on to have typical pregnancies after further testing. If your result shows increased risk, additional diagnostic testing can provide more definitive information, and it's worth discussing timing with your prenatal care schedule.
How often should I retest?
This is a one-time screening tied to a specific window in pregnancy (10.0-13.9 weeks), so it isn't something you retest later in the same pregnancy. If you're pregnant again in the future, you would complete this screen again during that pregnancy's first trimester window.
What should I do if my results are abnormal?
If your results show an increased risk, the report will explain what your specific value means and what the recommended next steps are, which often includes additional diagnostic testing for more definitive answers. Try not to assume the worst — many increased-risk results do not confirm a diagnosis. If you have any urgent symptoms like heavy bleeding or severe pain, seek medical care right away regardless of your screening results.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
hCG (Human Chorionic Gonadotropin) 1.2 MoM
Demo results
Low Risk Expected Range High Risk
1.2 MoM

What this means

This value falls within the expected range for hCG at this stage of pregnancy, which contributes to a lower calculated risk for Down Syndrome and Trisomy 18. Values are reported as a multiple of the median (MoM) and combined with other markers for a full risk estimate. A result in this range does not guarantee a typical outcome, but it's a reassuring sign.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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First Trimester Screen — Down Syndrome Risk Test

  • Screen for early pregnancy chromosomal risk
  • Check baby's Down Syndrome risk early
  • Assess Trisomy 18 risk factors
$493
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.