What's this test for?

This test is ideal if you're of Ashkenazi Jewish descent and want to know whether you carry a factor XI gene mutation that can cause excessive bleeding. It's especially useful if you have a family history of bleeding problems, easy bruising, or are planning a surgery or dental procedure and want to understand your bleeding risk ahead of time. Knowing your status helps you and any medical team prepare properly before a procedure.

What's included in this test?

This test looks specifically for genetic mutations in the factor XI gene that are common among people of Ashkenazi Jewish ancestry. These mutations affect a protein your body needs to form normal blood clots, so identifying them helps explain unexplained bruising or bleeding and flags extra bleeding risk before surgery.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding means. If a mutation is found, a simple next step is to share this information before any future surgery or dental work so extra precautions can be taken, and family members may want to consider testing too since this condition can run in families. You can download a standard lab report directly from your account at any time. Since this is a one-time genetic result, tracking over time isn't needed the way it is for other blood values.

Who should consider this test?

This test is a good fit for anyone of Ashkenazi Jewish heritage, especially if you have relatives with a known bleeding disorder or if you've personally experienced unusually heavy bleeding after dental work, childbirth, or a minor injury. It's also worth considering before a planned surgery so you can plan ahead with your care team. People with no family history or symptoms may still choose to test simply because the mutation is more common in this ancestry group.

What symptoms indicate I may need this test?

Watch for things like frequent nosebleeds, heavy or prolonged bleeding from small cuts, easy bruising, unusually heavy periods, or excessive bleeding after a tooth extraction or minor surgery. If a close relative has been diagnosed with a factor XI deficiency, that's also a strong reason to test even without symptoms. These clues suggest your blood may not be clotting as efficiently as it should.

What is factor XI deficiency and why does it matter?

Factor XI is one of several proteins your blood needs to form a stable clot and stop bleeding. When the gene that makes this protein has a mutation, your blood may take longer to clot, which usually isn't noticeable in daily life but can become a real problem during surgery, childbirth, or an accidental injury. Knowing you carry this mutation ahead of time lets you and any care team plan extra precautions, like having clotting support on hand during a procedure.

What does it mean if my result is positive?

A positive result means you carry one or more copies of a factor XI gene mutation, which puts you at increased risk for prolonged bleeding, particularly during surgical or dental procedures. This doesn't mean you'll definitely have a bleeding problem, but it's important information to share before any planned procedure. Simple steps like informing your surgical team in advance and asking about clotting-factor support can reduce risk significantly.

What causes this mutation and can it be inherited?

Factor XI mutations are inherited, meaning they're passed down from parents to children through genes rather than being caused by lifestyle or diet. These specific mutations are found more often in people of Ashkenazi Jewish ancestry due to shared genetic history within that population. If you test positive, siblings, parents, and children may want to consider testing as well.

How often should I retest?

Since this is a genetic test looking at mutations you're born with, your result won't change over time, so retesting isn't necessary once you have a clear result. The only reason to test again would be to confirm an old result using a newer method, or if a family member's diagnosis prompts you to double check. Your one-time result stays relevant for life.

What should I do if my results are abnormal?

If your result shows a mutation, keep a copy of your report handy and share it before any future surgery, dental procedure, or childbirth so extra clotting precautions can be arranged in advance. Consider letting close biological relatives know, since they may carry the same mutation and benefit from testing. If you experience unusually heavy or hard-to-stop bleeding at any point, seek medical care right away.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Factor XI Mutation Test - Ashkenazi Jewish Bleeding Risk

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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