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Genetic test for Factor VII mutation linked to family clotting or bleeding history

Factor VII R353Q Genetic Test for Clotting Risk

Factor VII R353Q Mutation Analysis

  • Screen for inherited blood clotting risk
  • Check family history clotting factors
  • Assess genetic thrombosis protection markers
$1510
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're concerned about your risk for blood clots, especially if clotting or bleeding disorders run in your family. It looks at a specific genetic change in the Factor VII gene that plays a role in how your blood clots. Many people order this test after a family member has been diagnosed with a clotting condition or after an unexplained clotting event of their own.

What's included in this test?

This test checks specifically for the R353Q variant in the Factor VII gene, a gene involved in one of the key steps of blood clot formation. Factor VII is a protein made in the liver that helps trigger clotting when your body needs to stop bleeding, and certain variants in this gene can affect how strongly or weakly your blood clots.

What happens after I get my results?

Your results will show up securely in your account, with a clear explanation of what your specific result means. If your result shows the protective R353Q variant, there's generally no action needed beyond sharing this information for family health planning purposes. A standard lab report is available to download anytime from your account, and since this is a one-time genetic result, there's no need for retesting or trend tracking like with other blood markers. If you have a personal or family history of unexplained clotting or bleeding, this result can be useful context to bring up during any future health discussions.

How can I naturally support healthy blood clotting?
Staying hydrated, moving regularly, and avoiding long periods of sitting can help support healthy circulation and normal clotting function. Eating a balanced diet with foods rich in vitamin K, like leafy greens, supports the proteins involved in clotting. Avoiding smoking and managing your weight can also lower your overall risk for clotting problems, regardless of your genetic makeup.
When will I get my results?
Results for this genetic test are typically ready within about 7 days after your sample is collected. You'll get a notification once they're posted to your account, where you can view and download the full report.
Who should consider this test?
This test is worth considering if you have a close family member with a known clotting disorder, a personal history of unexplained blood clots, or a family history of early heart attacks or strokes. It can also be useful for people who want more insight into their genetic clotting risk before starting hormone therapy or long trips that involve prolonged sitting. If you're unsure whether it applies to you, reviewing your family health history is a good first step.
What symptoms indicate I may need this test?
Signs like unexplained leg swelling, pain, or warmth (which can indicate a clot), unexplained bruising, or a family history of clotting events are all reasons someone might consider this test. Recurrent miscarriages have also been linked to clotting factor issues in some cases. If you've experienced any of these along with a family history of clotting conditions, this test can add useful information.
What is the Factor VII R353Q variant and why does it matter?
The R353Q variant is a small change in the Factor VII gene that has been linked to lower Factor VII activity in the blood. Because Factor VII helps trigger the clotting process, having this variant may actually lower your risk of forming unwanted blood clots. Understanding whether you carry this variant can add helpful context to your overall cardiovascular and clotting risk picture.
What causes changes in Factor VII activity?
Factor VII activity can be influenced by genetics, including variants like R353Q, as well as by liver health since Factor VII is made in the liver. Certain medications, vitamin K levels, and other health conditions can also raise or lower Factor VII activity. This genetic test specifically looks at the inherited component of that picture.
What should I do if my results show a clotting-related risk factor?
If your results suggest a different variant associated with increased clotting risk, focus on the lifestyle habits you can control, like staying active, maintaining a healthy weight, and avoiding smoking. Let close family members know, since genetic clotting factors can run in families. If you notice any signs of an active clot, such as sudden leg swelling, chest pain, or shortness of breath, seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Factor VII R353Q Genotype Negative (R/R - No Q Variant Detected)
Demo results
Variant Detected (Q Allele) No Variant Detected (R/R)
Negative (R/R - No Q Variant Detected)

What this means

A 'negative' result means you don't carry the R353Q variant and have the typical R/R genotype for this gene. This doesn't change your overall clotting risk based on this particular factor. A 'positive' result means you carry at least one copy of the Q allele, which has been linked to lower Factor VII activity and a potentially reduced risk of thrombosis.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Factor VII R353Q Genetic Test for Clotting Risk

  • Screen for inherited blood clotting risk
  • Check family history clotting factors
  • Assess genetic thrombosis protection markers
$1510
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.