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Genetic clotting risk test for people with family history of blood clots

Factor V Leiden Genetic Blood Clot Risk Test

Factor V (Leiden) Mutation Analysis with Reflex to HR2 Mutation Analysis

  • Detect inherited blood clot risk
  • Assess family history clotting concerns
  • Screen for recurrent clot causes
$1281
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained blood clots, or if you have a personal or family history of blood clots (also called venous thromboembolism). It's especially useful if you had a clot before age 50, a clot in an unusual location, or if clots run in your family. Identifying a genetic clotting risk factor can help guide decisions about prevention and long-term care.

What's included in this test?

This test looks at a specific gene change linked to blood clotting risk, and if a certain pattern is found, it automatically checks a second related gene change for a more complete risk picture. Together, these results help explain whether your body has a higher tendency to form abnormal blood clots, which is useful information for you and your family.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative result means for this specific genetic variant. If you test positive, next steps typically include discussing clot-prevention strategies during high-risk situations like surgery, pregnancy, or long flights, and letting blood relatives know since this condition can run in families. A downloadable lab report is available in your account, and since this is a one-time genetic result, tracking over time isn't usually needed, though you can keep the report on file for future reference.

How can I naturally support healthy blood flow and clotting balance?
Staying active, avoiding long periods of sitting or immobility, and staying well-hydrated can all help support healthy circulation. Maintaining a healthy weight and avoiding smoking are also important since both can raise clotting risk. If you carry a genetic clotting risk factor, moving around during long trips and following any pre-surgery guidance closely can make a real difference.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed. Genetic tests like this one can take a bit longer than routine bloodwork because of the specialized lab analysis involved. You'll get a notification as soon as your results are posted to your account.
Who should consider this test?
This test is a good option for anyone who has had a blood clot at a young age, an unusual clot location, or repeat clots. It's also worth considering if a close family member has been diagnosed with Factor V Leiden or another inherited clotting disorder. People with a strong family history of blood clots, even without symptoms themselves, may also want this information.
What symptoms indicate I may need this test?
Symptoms like leg swelling, pain, redness, or warmth (especially in one leg) can signal a blood clot and may prompt this kind of testing. Sudden shortness of breath or chest pain can also indicate a clot has traveled to the lungs, which is a medical emergency requiring immediate care. If you've had any of these symptoms before, especially more than once, this test can help explain why.
What does a positive result mean?
A positive result means you carry one or two copies of the Factor V Leiden gene change, which increases your risk of developing abnormal blood clots. Having one copy raises risk moderately, while having two copies raises it much more significantly. This doesn't mean you will definitely get a clot, but it does mean extra precautions are worth taking during higher-risk times like surgery, pregnancy, or prolonged immobility.
What causes this genetic clotting risk?
This condition is inherited, meaning it's passed down from a parent through a specific change in the gene that makes a blood clotting protein. It's not caused by lifestyle or diet choices. Because it's genetic, siblings, parents, and children of someone who tests positive may also want to consider testing.
What should I do if my results are positive?
If you test positive, keep a copy of your results and share the information with blood relatives who may want to get tested too. Take extra precautions during high clot-risk situations, such as long-distance travel, surgery, or pregnancy, like moving frequently and staying hydrated. If you ever notice sudden leg swelling, pain, chest pain, or shortness of breath, seek medical care right away since these can be signs of a dangerous clot.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
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Fast & confidential, we never sell or share your data
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Demo results
Factor V Leiden Mutation Heterozygous Positive
Demo results
Negative Positive
Heterozygous Positive

What this means

A heterozygous positive result means you carry one copy of the Factor V Leiden gene change, which raises your risk of developing abnormal blood clots by about 6 to 8 times compared to someone without the variant. This doesn't mean a clot is certain, but it's important information for managing risk during situations like surgery, pregnancy, or long periods of immobility.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Factor V Leiden Genetic Blood Clot Risk Test

  • Detect inherited blood clot risk
  • Assess family history clotting concerns
  • Screen for recurrent clot causes
$1281
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.