What's this test for?

This test is ideal if you're concerned about your risk of dangerous blood clots, especially if you already know you carry the Factor V Leiden mutation or have close relatives who do. It's also useful if you or your family have a history of unexplained blood clots, miscarriages, or clotting problems during pregnancy. Knowing whether you carry this additional gene variant helps you and your family understand your personal clotting risk.

What happens after I get my results?

Your result will appear in your account showing whether the HR2 allele was detected, along with a simple explanation of what that means. If you carry this variant, especially alongside Factor V Leiden, practical next steps include discussing blood clot prevention strategies for situations like surgery, long flights, or pregnancy, and staying alert for symptoms like leg swelling or pain. You can download a standard lab report from your account at any time, and since this is a one-time genetic result, there's no need to retest, though you can keep the report saved in your trends history for future reference.

Who should consider this test?

This test is a good fit for people who already tested positive for Factor V Leiden and want to know their full clotting risk picture. It's also worth considering if you have a personal or family history of blood clots (deep vein thrombosis or pulmonary embolism), recurrent miscarriages, or if a close relative has been found to carry the HR2 allele. Since this is a genetic test, testing once is generally enough for your lifetime risk assessment.

What symptoms indicate I may need this test?

Signs that may point to a clotting risk worth investigating include swelling, warmth, or pain in one leg, unexplained shortness of breath, or chest pain that could suggest a clot in the lungs. Recurrent pregnancy loss or a clot that happened at a young age or without an obvious cause are also reasons to look into inherited clotting factors. If you're experiencing sudden severe leg swelling or trouble breathing, seek medical care right away rather than waiting on test results.

When will I get my results?

Results for this genetic mutation analysis are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification once your report is available in your account. Since this is a specialized DNA test, it takes a bit longer than routine blood work, so plan accordingly if you need results for an upcoming medical decision like surgery or pregnancy planning.

How can I naturally support healthy blood clotting balance?

While you can't change your genes, you can lower your overall clotting risk with everyday habits like staying active, avoiding long periods of sitting (especially on flights or car rides), and staying well hydrated. Maintaining a healthy weight and not smoking also meaningfully reduce clot risk. Some people find that gentle movement breaks every hour during travel and wearing compression socks on long trips are simple, practical habits worth adopting.

What is Factor V HR2 and why does it matter?

Factor V HR2 is a variation in the same gene responsible for the more well-known Factor V Leiden mutation, both of which affect how your blood clots. On its own, HR2 has a small effect on clotting risk, but when someone also carries the Factor V Leiden mutation, having both together raises the risk of dangerous blood clots (venous thrombosis) by about 3 to 4 times compared to Leiden alone. This matters because knowing your combined genetic risk can guide precautions around surgery, pregnancy, and long periods of immobility.

What does a positive HR2 result mean?

A positive result means you carry this gene variant, which by itself usually causes only a mild increase in clotting tendency. However, if you also carry Factor V Leiden, the combination substantially raises your risk of developing blood clots in the veins. It's worth sharing this information whenever you're preparing for surgery, starting hormone therapy, or planning a pregnancy, since these situations naturally increase clotting risk.

How often should I retest?

Since this is a DNA test looking at a gene variant you're born with, your result will never change, so there's no need to retest. You only need to take this test once in your lifetime. Keep a copy of your report handy for future reference, such as before surgeries or when discussing family planning.

What should I do if my results show I carry this variant?

If you test positive, especially in combination with Factor V Leiden, practical steps include avoiding prolonged immobility, staying active, and being extra mindful of clot symptoms after surgery, injury, or during pregnancy. Let any relevant care team know about your genetic result before major procedures so appropriate precautions can be taken. Sharing this information with blood relatives can also help them understand their own potential risk, since this variant runs in families.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Factor V HR2 Test - Blood Clot Risk Gene Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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