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Comprehensive muscle inflammation antibody testing for diagnosing autoimmune muscle disorders

Blood Test for Muscle Weakness and Inflammation

Extended Myositis Specific Antibody (MSA) Panel

Google
3,138 reviews
  • Checks for muscle inflammation markers.
  • Identifies specific muscle-related antibodies.
  • Helps diagnose muscle inflammation disorders.
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained muscle weakness, fatigue, difficulty climbing stairs or lifting objects, or persistent muscle pain that doesn't improve with rest. It helps identify specific antibodies associated with inflammatory muscle diseases like polymyositis and dermatomyositis, which are autoimmune conditions where your immune system attacks your muscle tissue. Many people use this test when they have ongoing muscle symptoms that haven't been explained by other tests, or when their doctor suspects an autoimmune muscle disorder.

How should I prepare for this test?

This is a simple blood test that typically requires no special preparation. You don't need to fast before the test, and you can take your regular medications unless your doctor specifically instructs otherwise. It's helpful to stay well-hydrated before your blood draw and wear clothing with sleeves that can be easily rolled up. If you're currently taking immunosuppressive medications, inform your healthcare provider as this may affect interpretation of results.

What's included in this test?

This extended panel screens for multiple myositis-specific antibodies that are markers of different types of inflammatory muscle diseases. Each antibody provides clues about which specific autoimmune condition might be present, how severe it may be, and what other organs might be affected. Together, these measurements help doctors distinguish between different forms of myositis and create targeted treatment plans based on your specific antibody profile.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your antibody results mean for your muscle health and whether specific autoimmune markers were detected. These notes include personalized recommendations like whether you need follow-up with a rheumatologist or neurologist, potential treatment options, and lifestyle modifications to manage symptoms. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially helpful for monitoring disease activity if you're diagnosed with myositis.
When will I get my results?
Because this is a specialized antibody panel, results typically take 7-14 business days to process. The extended timeframe is due to the sophisticated testing required to identify these specific autoimmune markers. You'll receive an email notification as soon as your results are ready, and you can access them securely through your online account along with the detailed doctor notes explaining what they mean.
Who should consider getting this test?
This test is important for anyone experiencing progressive muscle weakness, especially in the shoulders, hips, or thighs, or skin rashes combined with muscle symptoms. It's particularly relevant if you have difficulty with everyday activities like getting out of a chair, reaching overhead, or swallowing. People with a family history of autoimmune diseases or those who've had other tests showing elevated muscle enzymes should also consider this panel.
What symptoms indicate I may need this test?
Common symptoms include muscle weakness that gets worse over weeks or months, particularly in your upper arms and thighs. You might notice trouble climbing stairs, lifting groceries, or raising your arms above your head. Other signs include unusual fatigue that doesn't improve with rest, difficulty swallowing, shortness of breath during light activity, or skin changes like a purple-red rash on your eyelids or knuckles. If you experience persistent muscle pain along with these symptoms, this test can help identify the underlying cause.
How can I naturally support my muscle health?
While autoimmune muscle conditions typically require medical treatment, you can support your overall muscle health through gentle, regular movement and physical therapy exercises tailored to your abilities. Focus on an anti-inflammatory diet rich in omega-3 fatty acids from fish, colorful vegetables, and antioxidant-rich fruits. Prioritize quality sleep and stress management through meditation or gentle yoga, as stress can trigger autoimmune flares. Always work with your healthcare team before starting any new exercise program if you have muscle inflammation.
What are myositis-specific antibodies and why do they matter?
Myositis-specific antibodies are immune proteins that your body produces when it mistakenly attacks your own muscle tissue. Each type of antibody is associated with different patterns of muscle involvement, disease severity, and response to treatment. Detecting these specific antibodies helps doctors accurately diagnose which type of inflammatory muscle disease you have, predict potential complications, and choose the most effective treatment approach for your specific condition.
What happens if my results are positive for myositis antibodies?
If your test shows positive antibodies, it indicates your immune system is producing markers associated with inflammatory muscle disease. Your doctor will review your results along with your symptoms, physical examination, and possibly additional tests like muscle enzymes or imaging. Treatment typically involves working with a rheumatologist who specializes in autoimmune conditions and may include medications to reduce inflammation and suppress the immune response. Early detection and treatment can help prevent permanent muscle damage and improve your long-term outlook.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Anti-Jo-1 Antibody Negative
Demo results
Negative Positive
Negative

What this means

Your Anti-Jo-1 antibody test came back negative, meaning this specific marker for inflammatory muscle disease was not detected. This is a normal result and suggests that this particular type of autoimmune myositis is not present.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Muscle Weakness and Inflammation

Google
3,138 reviews
  • Checks for muscle inflammation markers.
  • Identifies specific muscle-related antibodies.
  • Helps diagnose muscle inflammation disorders.

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.