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Estrogen receptor IHC test for breast cancer tissue prognosis and therapy guidance

Estrogen Receptor (ER) Breast Cancer Tissue Test

Estrogen Receptor (ER), IHC with Interpretation

  • Assess breast tumor hormone sensitivity
  • Guide hormone therapy treatment decisions
  • Screen for cancer prognosis factors
$1003
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you or someone you're caring for has been diagnosed with breast cancer and needs more information about the tumor tissue itself. It looks at whether the cancer cells have estrogen receptors, which helps determine if hormone-based treatments are likely to work. This test is typically ordered after a biopsy or tissue sample has already been collected.

What's included in this test?

This test analyzes breast tumor tissue using a lab technique called immunohistochemistry (IHC) to detect estrogen receptors on cancer cells. Knowing whether these receptors are present helps explain how the cancer may behave and whether it could respond to hormone-blocking treatments. The pathologist's interpretation is included so the result is put into clinical context, not just a raw number.

What happens after I get my results?

Your results will appear in your account with a clear explanation of what a positive or negative estrogen receptor finding means. Next steps depend on the result: a positive finding often means hormone therapy may be a treatment option worth discussing further, while a negative finding points toward other treatment paths. You can download the full lab report from your account at any time, and if additional tissue markers are tested later, you can track results over time using the trends feature.

How can I naturally support hormone balance during cancer treatment?
While no natural remedy replaces cancer treatment, some everyday habits may support overall hormone balance and well-being. Eating a diet rich in vegetables, fiber, and lean protein, staying physically active as tolerated, managing stress, and limiting alcohol are commonly recommended supportive steps. Always pair any lifestyle changes with the guidance already provided by your treatment plan.
When will I get my results?
Results for this test are typically ready within about 7 days, since tissue samples require careful lab processing and expert interpretation. You'll receive a notification as soon as your results are posted to your account. Because this involves detailed tissue analysis, it takes longer than a standard blood test.
Who should consider this test?
This test is meant for people who have already been diagnosed with breast cancer and have tissue available from a biopsy or surgery. It's especially relevant if treatment planning requires knowing whether the tumor is hormone-receptor positive or negative. It is not a general screening test for people without a cancer diagnosis.
What does a positive estrogen receptor result mean?
A positive result means the cancer cells have receptors that respond to estrogen, which can act like fuel for tumor growth. This is actually useful information because it means hormone-blocking treatments may help slow or stop the cancer's growth. Many people with hormone-receptor-positive breast cancer have effective treatment options built around this finding.
What does a negative estrogen receptor result mean?
A negative result means the cancer cells don't rely on estrogen to grow, so hormone-blocking treatments generally won't be effective for this particular tumor. This finding helps steer treatment planning toward other approaches, such as chemotherapy or targeted therapies. It's simply a different biological profile, not a better or worse diagnosis on its own.
How often should I retest?
Estrogen receptor testing is usually a one-time test performed on an initial tissue sample rather than something retested on a routine schedule. If a tumor recurs or new tissue becomes available, retesting may be considered to check whether the receptor status has changed over time. Follow the guidance provided with your specific diagnosis and treatment timeline.
What should I do if my results are abnormal?
If your result comes back positive or negative, use the detailed report notes in your account to understand exactly what it means for treatment planning. Bring the report to any treatment discussions so it can be factored into next steps. If you have urgent symptoms or concerns, seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
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Demo results
Estrogen Receptor (ER) Status Positive
Demo results
Negative Positive
Positive

What this means

A positive result means the tumor cells carry receptors that respond to estrogen, which can drive cancer growth. This finding is useful because it means hormone-blocking treatments may be an effective part of the treatment plan.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Estrogen Receptor (ER) Breast Cancer Tissue Test

  • Assess breast tumor hormone sensitivity
  • Guide hormone therapy treatment decisions
  • Screen for cancer prognosis factors
$1003
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.