What's this test for?

This test is ideal if you're following up on a prostate biopsy and need more clarity about whether cancer cells are present. It helps pathologists tell the difference between benign prostate tissue and cancerous changes by looking for a specific protein marker. It's typically used alongside other findings, not as a standalone screening test.

What's included in this test?

This test looks specifically for ERG protein expression in tissue samples using an immunohistochemistry (IHC) technique. ERG expression matters because it's strongly linked to a chromosomal change (TMPRSS2-ERG translocation) found in a large share of prostate cancers, and it helps distinguish cancerous tissue from normal or pre-cancerous prostate tissue.

What happens after I get my results?

Your results will be available in your account, along with an explanation of what the ERG marker result means for your sample. Because this is a specialized tissue marker test tied to a biopsy, next steps usually involve reviewing the full pathology picture rather than lifestyle changes or retesting on a schedule. The standard lab report is downloadable from your account, and you can track this result alongside any other related results over time using the trends feature. If your result raises concerns, consider it a starting point for further evaluation rather than a final answer on its own.

How can I naturally support prostate health?

While this test measures a specific cancer-related marker that lifestyle changes won't reverse, general prostate health can benefit from a diet rich in vegetables, tomatoes, and healthy fats, along with regular physical activity. Limiting red meat and processed foods, staying at a healthy weight, and not smoking are also linked to better prostate outcomes. These habits support overall health but don't replace the need for proper tissue evaluation when cancer is a concern.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed, since this is a specialized pathology test that requires careful lab analysis. You'll be notified as soon as your report is available in your account. Because this test involves interpretation by a pathologist, it can take a bit longer than routine blood work.

Who should consider this test?

This test is most relevant for men who have already had a prostate biopsy and need additional clarity on ambiguous or borderline findings. It's also used when distinguishing between benign prostatic changes, PIN (a pre-cancerous condition), and actual prostate cancer. It's not a first-line screening test for the general population.

What symptoms indicate I may need this test?

On its own, ERG testing isn't ordered based on symptoms — it's used after a biopsy has already been taken. However, symptoms that might lead to a biopsy in the first place include difficulty urinating, blood in urine or semen, pelvic discomfort, or an elevated PSA level found on routine bloodwork. If you're experiencing these, a biopsy — not this marker test alone — would typically come first.

What is the ERG marker and why does it matter?

ERG is a protein that shouldn't normally show up in healthy prostate tissue, but it becomes active when a specific genetic change happens inside cancer cells. This genetic change, called the TMPRSS2-ERG translocation, is found in roughly half to two-thirds of prostate cancers, making ERG a useful clue for pathologists. Seeing ERG expression in a tissue sample helps confirm that cancerous changes are present rather than normal or benign tissue.

What does a positive ERG result mean?

A positive ERG result means the protein was detected in your tissue sample, which strongly suggests the presence of prostate cancer cells rather than benign tissue. It's considered a highly specific finding, meaning it's rarely seen in normal prostate tissue or in cancers from other organs. This result is generally interpreted together with other pathology findings to guide next steps.

What should I do if my results are abnormal?

If your ERG result comes back positive, treat it as an important piece of a larger puzzle rather than a standalone diagnosis. The full pathology report, including tumor grade and other markers, will give a much clearer picture of what's going on. Discussing the complete report with whoever is coordinating your care is the most useful next step, and keeping a copy of your downloadable report for your records is a good idea.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

ERG IHC Test - Prostate Cancer Tissue Marker

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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