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EGFR mutation test for lung cancer patients considering targeted therapy options

EGFR Mutation Test for Lung Cancer Treatment Planning

Epidermal Growth Factor Receptor (EGFR) Mutation Analysis

  • Detect EGFR gene mutation status
  • Guide targeted lung cancer therapy
  • Screen for treatment resistance mutations
$2900
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you've been diagnosed with lung adenocarcinoma and need to know whether targeted therapy could work for you. It's especially relevant if you're a younger patient without a smoking history, since EGFR mutations show up more often in that group. It also helps if your cancer has come back after treatment, since it can reveal a specific resistance mutation that changes which drugs may still work.

What's included in this test?

This test looks for specific genetic changes in the EGFR gene that are found in a portion of lung cancers. It checks the parts of the gene where the vast majority of these mutations occur, plus a specific change linked to treatment resistance, giving a fuller picture of whether targeted lung cancer drugs are likely to help.

What happens after I get my results?

Your results will be available in your account, with each finding explained in plain language so you understand what mutation status was found. If a mutation is detected, the report will note which specific change was identified, including whether the T790M resistance mutation is present, which is important information for choosing next treatment steps. The full lab report can be downloaded from your account at any time, and if you're retested later during treatment, you can track changes in your results over time using the trends feature. Because this result directly affects cancer treatment decisions, share it with your treatment team as soon as it's available.

How can I naturally support my body during lung cancer treatment?
While no lifestyle change replaces targeted therapy, eating a nutrient-dense diet, staying hydrated, and getting light physical activity as tolerated can help you handle treatment better. Prioritizing sleep and stress reduction, such as gentle breathing exercises, may support your overall well-being during this time. Avoid smoking or secondhand smoke exposure entirely, since this can worsen outcomes. Always pair these habits with the treatment plan you and your care team have agreed on.
When will I get my results?
Results for this test are typically ready within about 7 days after your sample is processed at the lab. Because this is a specialized genetic test, it takes longer than routine bloodwork. You'll be notified as soon as your results are posted to your account.
Who should consider this test?
This test is most relevant for people already diagnosed with lung adenocarcinoma, especially those who are younger, have never smoked, or whose cancer has an unclear cause. It's also useful for patients whose cancer has returned or stopped responding to previous targeted therapy, since it can detect the T790M resistance mutation. It is not a general screening test for people without a cancer diagnosis.
What symptoms might lead someone to need this test?
People are usually referred for this test after imaging or a biopsy has already confirmed lung adenocarcinoma. Symptoms that led to that diagnosis often include a persistent cough, unexplained weight loss, chest pain, or shortness of breath. If your cancer has started progressing again after initial treatment, that's also a common reason to test for the resistance mutation.
What is an EGFR mutation and why does it matter?
EGFR is a protein on the surface of cells that helps control cell growth. In some lung cancers, a mutation in the gene that makes this protein causes cells to grow out of control. Knowing whether this mutation is present matters because certain drugs are designed specifically to block this abnormal signal, and they tend to work much better in patients whose tumors carry the mutation.
What does a positive EGFR mutation result mean?
A positive result means your tumor carries a change in the EGFR gene that is known to respond well to targeted kinase inhibitor drugs. This is generally seen as helpful information because it opens up treatment options that specifically target this mutation rather than relying only on standard chemotherapy. If the T790M resistance mutation is found instead, it means newer generation targeted drugs designed to overcome that resistance may be effective.
How often should I retest for EGFR mutations?
Retesting is usually considered if your cancer starts progressing again after a period of responding to targeted therapy, since this can signal a new resistance mutation has developed. It's not a test you repeat on a routine schedule like a wellness panel. Discuss timing for any follow-up test with your treatment plan.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
EGFR Mutation Status (Exons 18-21, including T790M) Positive - Exon 19 Deletion Detected
Demo results
Negative (No Mutation Detected) Positive (Mutation Detected)
Positive - Exon 19 Deletion Detected

What this means

A positive result means a mutation was found in the EGFR gene, specifically an exon 19 deletion, which is one of the most common mutations linked to lung adenocarcinoma. This finding suggests the tumor may respond well to EGFR-targeted kinase inhibitor drugs. If retested later and the T790M mutation appears, it would indicate acquired resistance to current therapy.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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EGFR Mutation Test for Lung Cancer Treatment Planning

  • Detect EGFR gene mutation status
  • Guide targeted lung cancer therapy
  • Screen for treatment resistance mutations
$2900
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.