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Urine drug monitoring test for tricyclic antidepressant treatment compliance and dosage tracking

Tricyclic Antidepressant Urine Drug Monitoring Test

Drug Monitoring, Tricyclic Antidepressants, Quantitative, Urine

  • Confirm antidepressant medication compliance accurately
  • Track nortriptyline and amitriptyline levels consistently
  • Monitor treatment adherence over time
$505
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're currently prescribed amitriptyline or nortriptyline for depression or chronic nerve pain and need to confirm you're taking your medication as directed. It's also useful if you or someone monitoring your treatment wants to verify compliance with a prescribed drug regimen. This test does not tell you the dose you're taking, only whether the drugs and their breakdown products are present in your urine.

What's included in this test?

This test measures both amitriptyline and its active metabolite nortriptyline in your urine using a precise lab method called LC/MS/MS. Looking at both the parent drug and its metabolite together gives a fuller picture of how your body is processing the medication and whether it's being taken as prescribed. This combination helps distinguish genuine compliance issues from normal variations in individual drug metabolism.

What happens after I get my results?

Your results will show up in your account with the quantitative levels of amitriptyline and nortriptyline detected, along with an explanation of what those numbers mean. If your results don't match what's expected based on your prescribed treatment, the next step is usually a conversation about medication adherence and possibly a repeat test to confirm the pattern. A standard lab report is available to download from your account at any time, and you can track results over multiple tests using the trends feature to see patterns over time.

How can I naturally support healthy medication metabolism?
Staying well hydrated helps your kidneys process and clear medications like tricyclic antidepressants more consistently, which can make monitoring results more reliable. Taking your dose at the same time each day, avoiding alcohol, and not skipping or doubling doses all help keep drug levels steady and predictable. Eating regular meals and maintaining a consistent routine also supports steady metabolism, since erratic eating or sleep patterns can affect how your body processes medications.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification and can log into your account to view the detailed report as soon as it's available. If timing is urgent, it's worth checking your order confirmation for any specific guidance on this particular test.
Who should consider this test?
Anyone currently taking amitriptyline or nortriptyline as part of a depression or chronic pain treatment plan may want to consider this test, especially if adherence to the prescribed regimen needs to be confirmed. It's also relevant for situations where treatment isn't working as expected and there's a need to check whether the medication is actually being taken consistently. This test is a good next step when you want an objective record of medication use over time.
What symptoms indicate I may need this test?
If your depression or nerve pain symptoms aren't improving despite being on amitriptyline or nortriptyline, it may be worth checking whether the medication is actually present in your system at expected levels. Signs like inconsistent symptom control, unexpected side effects, or concerns about missed doses are also good reasons to consider this test. It's a useful check when there's a mismatch between how you're supposed to be responding to treatment and how you actually feel.
What does it mean if my results are higher than expected?
Higher-than-expected levels of amitriptyline or nortriptyline in your urine could mean you're taking more than the prescribed dose, taking doses too close together, or that your body is metabolizing the drug differently than average. This is worth noting because higher levels can sometimes come with more pronounced side effects like drowsiness, dry mouth, or dizziness. If you notice unusual symptoms along with a high result, it's a good idea to review your dosing schedule and consider seeking medical care if symptoms feel severe.
What does it mean if my results are lower than expected?
Lower-than-expected levels can suggest that doses are being missed, taken irregularly, or that the medication is being processed and cleared faster than typical. It could also mean the sample was collected shortly after starting the medication, before levels have built up. If low levels are unexpected, it's worth double-checking your dosing routine and the timing of your last dose relative to the urine collection.
How often should I retest?
Retesting frequency depends on your specific treatment plan and monitoring needs, but many people on ongoing therapeutic drug monitoring retest periodically, such as every few months, to confirm consistent adherence. If a result comes back unexpected, a follow-up test soon after can help clarify whether it was a one-time issue or an ongoing pattern. Using the trends feature in your account can help you and anyone involved in your care decide on the right retesting schedule.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Amitriptyline + Nortriptyline (Total) 185 ng/mL
Demo results
Not Detected / Below Expected Within Expected Range
185 ng/mL

What this means

This result falls within the expected range for someone taking amitriptyline or nortriptyline as prescribed. It suggests consistent medication use around the time of sample collection. Quantitative levels alone can't confirm the exact dose taken, since individual metabolism varies.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Tricyclic Antidepressant Urine Drug Monitoring Test

  • Confirm antidepressant medication compliance accurately
  • Track nortriptyline and amitriptyline levels consistently
  • Monitor treatment adherence over time
$505
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.