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dsDNA antibody test for diagnosing and monitoring lupus autoimmune disease

dsDNA Antibody Test for Lupus Symptoms

DNA (ds) Antibody, Crithidia IFA with Reflex to Titer

  • Detect lupus-related immune system activity
  • Monitor autoimmune disease flare patterns
  • Track joint pain and fatigue causes
$318
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing joint pain, unexplained fatigue, skin rashes, or other symptoms that may point to an autoimmune condition like lupus. It looks for a specific antibody your immune system may produce when it mistakenly attacks your own body's DNA. It's also useful if you've already been diagnosed with lupus and need to track how active the disease is.

What's included in this test?

This test measures a single, highly specific antibody category that's closely tied to lupus disease activity. It matters because this antibody rises and falls with flares of the disease, making it one of the most useful markers for tracking whether lupus is active or under control.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what a normal versus abnormal range looks like for this antibody. If your result is positive, next steps typically include retesting or additional follow-up testing to confirm disease activity, since this antibody can fluctuate over time. You can download a standard lab report directly from your account, and if you test again in the future, the trends feature lets you compare results side by side to see how things change.

How can I naturally support immune system balance?
While you can't control autoimmune antibody levels through lifestyle alone, reducing stress, getting consistent sleep, and eating an anti-inflammatory diet rich in fruits, vegetables, and omega-3s may help support overall immune balance. Limiting sun exposure is especially important if you have lupus, since UV light can trigger flares. Staying active with gentle exercise like walking or yoga can also help manage fatigue and joint stiffness.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as they're available in your account. If your initial result requires a reflex titer test, that additional step may add a little extra time before your final results are complete.
Who should consider this test?
This test is worth considering if you have symptoms like persistent joint pain, butterfly-shaped facial rash, unexplained fevers, or extreme fatigue that don't have an obvious cause. It's also recommended if you've already been diagnosed with lupus or mixed connective tissue disease and need to monitor how active your condition is over time. People with a family history of autoimmune disease and unexplained symptoms may also benefit.
What symptoms indicate I may need this test?
Common symptoms that suggest this test could help include joint pain and swelling, a facial rash that worsens with sun exposure, unexplained fatigue, low-grade fevers, and hair loss. Some people also notice mouth sores or sensitivity to sunlight. If several of these symptoms show up together and stick around for weeks, it may be worth investigating further.
What does a positive result mean?
A positive result means your immune system is producing antibodies that target your own DNA, which is strongly associated with active lupus. The higher the titer (the follow-up test that measures antibody concentration), the more likely it reflects active disease, particularly affecting the kidneys. This finding is usually paired with your symptoms and other lab work to get a fuller picture of what's going on.
How often should I retest?
If you have a confirmed lupus diagnosis, retesting every 3 to 6 months can help track how active your disease is, especially if your treatment plan has changed. If you're newly investigating symptoms and get a positive result, a follow-up titer test soon after is usually recommended to confirm the finding. Your retesting schedule may need to be more frequent during a flare-up.
What should I do if my results are abnormal?
If your result comes back positive, don't panic — this antibody can appear at low levels even in some healthy people. Focus on tracking your symptoms closely, avoid known lupus triggers like excessive sun exposure, and consider a follow-up titer test to get more detail on the antibody level. If you experience severe symptoms like significant swelling, chest pain, or difficulty breathing, seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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Get lab order in minutes, results come overnight*
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Demo results
dsDNA Antibody (Crithidia IFA) Negative
Demo results
Negative (Normal) Positive (Reflex to Titer)
Negative

What this means

A negative result means no significant dsDNA antibodies were detected, which is what's expected in most healthy people. This makes an active lupus flare involving dsDNA antibodies less likely at this time, though it doesn't fully rule out autoimmune disease if symptoms persist.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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dsDNA Antibody Test for Lupus Symptoms

  • Detect lupus-related immune system activity
  • Monitor autoimmune disease flare patterns
  • Track joint pain and fatigue causes
$318
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.