What's this test for?

This test is ideal if you're being treated for a cytomegalovirus (CMV) infection and your symptoms or viral levels aren't improving despite antiviral medication. It helps if you have a weakened immune system, such as after a transplant, and your CMV infection isn't responding the way it should to drugs like Ganciclovir or Foscarnet. It looks for specific gene changes in the virus that can cause it to resist treatment.

What's included in this test?

This test analyzes two key regions of the CMV virus's genetic material, called UL97 and UL54, because mutations in these areas are the most common cause of drug resistance. Checking both regions matters because different mutations affect different antiviral drugs, so the results help identify which medications are still likely to work against your specific virus.

What happens after I get my results?

Your results will be available in your account, with an explanation of what each finding means for your treatment options. If resistance mutations are found, the report will explain which drugs may be less effective, so this information can guide adjustments to your antiviral therapy plan. A downloadable standard lab report is also available directly from your account for your records. You can use the trends feature to track how your CMV status changes if you retest over time during treatment.

Who should consider this test?

This test is a good option for people undergoing treatment for CMV infection whose symptoms or viral load aren't improving as expected. It's especially useful for transplant recipients, people with weakened immune systems, or anyone on long-term antiviral therapy for CMV. If your current treatment doesn't seem to be working, this test can help figure out why.

When will I get my results?

Results are typically ready within about 7 days from when the lab receives your sample. This genetic analysis takes a bit longer than a standard blood test because it involves closely examining the virus's genetic code for specific mutations. You'll be notified as soon as your results are posted to your account.

What symptoms indicate I may need this test?

Signs that your current CMV treatment might not be working include ongoing fever, fatigue, or worsening symptoms despite being on antiviral medication for several weeks. Rising viral load numbers on repeat blood tests, even while on treatment, is another key indicator. If you have a weakened immune system and your CMV infection seems to be getting worse instead of better, this test can help explain why.

What is CMV drug resistance and why does it matter?

CMV drug resistance happens when the virus changes its genetic code in a way that lets it survive despite antiviral medication. This matters because it means the medicine you're taking may not be clearing the infection, which can allow the virus to keep multiplying and causing symptoms. Identifying resistance early helps guide a switch to a different, more effective antiviral option.

What causes CMV to become drug-resistant?

CMV resistance usually develops when the virus is exposed to antiviral drugs for a long period of time, giving it a chance to develop protective mutations as it copies itself. This is more common in people with weakened immune systems who need extended treatment courses. Not taking medication exactly as prescribed can also give the virus more opportunity to develop resistance.

How often should I retest?

Retesting is generally considered if your viral load isn't dropping as expected after a few weeks on antiviral treatment, or if symptoms return after initially improving. Your treatment plan and viral load trends will help determine the right timing for you. Tracking results over time in your account can help spot patterns that suggest resistance is developing.

What should I do if my results show resistance?

If your results show a resistance mutation, the report will indicate which antiviral drugs are likely affected, which can help inform a switch to an alternative treatment such as Maribavir, Cidofovir, or Letermovir. It's important to act on these results promptly since ongoing use of an ineffective drug allows the infection to continue. Keep monitoring your symptoms closely and seek immediate medical care if you notice worsening fever, confusion, or breathing difficulty, as these can signal a serious infection.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

CMV Genotype Test - Antiviral Resistance Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]