What's this test for?

This test is ideal if you're experiencing unexplained blistering, persistent skin rashes, or unusual sores that won't heal. It helps identify autoimmune skin conditions like blistering diseases, dermatitis herpetiformis, and skin vasculitis by examining a skin sample under a specialized microscope. It's also useful if you have signs of a connective tissue disorder showing up on your skin, such as lichen planus-like rashes or unexplained purple spots.

What happens after I get my results?

Your results will be available in your account, with an explanation of what each finding means. Depending on what's found, next steps may include retesting, monitoring for new symptoms, or taking the report to guide further care if a pattern suggests an autoimmune or inflammatory skin condition. If any finding suggests a rapidly worsening skin condition, seek medical care promptly. You can download the full lab report anytime and track any related results over time using the trends feature.

What's included in this test?

This test checks for immune deposits including IgG, IgA, IgM, fibrinogen, and the complement protein C3, along with a specialized C5b-9 marker used to distinguish similar autoimmune skin conditions. These antibodies and proteins build up in skin tissue during autoimmune reactions, and the specific pattern found helps identify conditions like blistering disorders, IgA-related vasculitis, and lupus- or dermatomyositis-related skin changes. Together, these findings help pinpoint which type of autoimmune or inflammatory skin issue may be causing your symptoms.

How can I naturally support healthy skin while dealing with autoimmune symptoms?

While this test looks for immune-related skin changes that need targeted evaluation, some everyday habits can support your skin's overall health. Keeping skin moisturized, avoiding known triggers like excess sun exposure or harsh soaps, eating an anti-inflammatory diet rich in fruits and vegetables, and reducing stress can help calm skin irritation. These steps won't replace targeted care but may reduce flare-ups while you figure out what's going on.

When will I get my results?

Results are typically ready within about 7 days after your sample is processed at the lab. Because this test involves detailed microscopic examination of skin tissue, it takes a bit longer than a standard blood test. You'll get a notification as soon as your results are available in your account.

Who should consider this test?

This test is a good option for people with unexplained blistering, chronic rashes, or skin sores that keep coming back without a clear cause. It's also useful for those with symptoms suggesting a connective tissue disorder, like joint pain paired with skin rashes or discoloration. If you've had ongoing, unexplained skin symptoms that haven't been figured out through basic exams, this test can offer more specific answers.

What symptoms indicate I may need this test?

Common symptoms include blisters or fluid-filled sores on the skin or in the mouth, intensely itchy bumps or rashes, purple or red spots that don't fade with pressure, and rashes that flare in sun-exposed areas. Persistent, unexplained skin sores that don't heal or keep coming back are also a signal. If you're dealing with any of these along with joint pain or fatigue, this test can help clarify what's happening.

What is dermatitis herpetiformis and why does it matter?

Dermatitis herpetiformis is an intensely itchy, blistering skin rash that's actually linked to gluten sensitivity, similar to celiac disease. It matters because catching it early can point you toward dietary changes, like cutting out gluten, that calm the skin and address the underlying gut-related trigger. Left unaddressed, it tends to come and go in cycles and can affect your quality of life.

What does a positive result on this test mean?

A positive result means the lab found antibody or protein deposits in your skin that are typically associated with an autoimmune or inflammatory skin condition. The specific pattern of deposits helps narrow down which condition is most likely, such as a blistering disease or a form of vasculitis. Your report will explain the pattern found and what it generally suggests, so you can decide on appropriate next steps.

How often should I retest?

Retesting isn't usually needed on a routine schedule for this test since it's typically used to investigate an active, unexplained skin issue rather than for ongoing monitoring. If your skin symptoms change significantly or a new area is affected after treatment, retesting a new skin sample may help confirm whether the underlying process has changed. Otherwise, this test is generally a one-time diagnostic step tied to your current symptoms.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Cutaneous Direct Immunofluorescence - Skin Disease Test

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Cutaneous Direct Immunofluorescence Skin Test