What's this test for?

This test is ideal if you're being evaluated for a rare blood disorder called atypical chronic myeloid leukemia (aCML) or chronic neutrophilic leukemia (CNL). It's also useful if you've already been diagnosed with a myeloid neoplasm and need more information about the specific genetic changes driving it. Your results can help explain unusual white blood cell counts or ongoing symptoms like fatigue, bone pain, or frequent infections that haven't been explained by other testing.

What's included in this test?

This test looks specifically at two sections of the CSF3R gene, called exon 14 and exon 17, which are the regions most commonly linked to abnormal blood cell growth in certain rare leukemias. Analyzing these specific gene regions helps identify a genetic driver behind unexplained white blood cell abnormalities, which can guide next steps for monitoring or further testing.

What happens after I get my results?

Your results will show up in your online account along with an explanation of what a positive or negative finding means for CSF3R mutations. If a mutation is found, the report will explain why this matters and what kind of monitoring or retesting is typically recommended for this type of finding. You can download a standard lab report directly from your account at any time, and if you test again in the future, you'll be able to track your results over time using the trends feature. Because this is a serious finding when positive, seeking prompt medical care is strongly recommended if your result comes back abnormal.

How can I naturally support healthy blood cell function?

While a genetic mutation like this can't be changed through lifestyle, you can support your overall blood and immune health with a nutrient-dense diet rich in leafy greens, lean protein, and whole grains. Staying well-hydrated, getting consistent sleep, and avoiding tobacco and excess alcohol also support healthy bone marrow function. Regular movement and stress management may help support your immune system, though they don't replace medical monitoring for a diagnosed mutation.

When will I get my results?

Results are typically available within about 7 days after your sample is processed at the lab. Because this test uses advanced DNA sequencing technology, it takes a bit longer than routine blood work, so plan accordingly. You'll get a notification as soon as your results are ready to view in your account.

Who should consider this test?

This test is generally considered by people who already have unexplained elevated white blood cell counts, especially neutrophils, that haven't been explained by infection or other common causes. It's also relevant for those with a suspected or confirmed diagnosis of a myeloid neoplasm who want more detail on the genetic mutations involved. People with a family history of rare blood cancers who have concerning symptoms may also consider this test.

What symptoms indicate I may need this test?

Symptoms that might prompt this test include unexplained fatigue, easy bruising or bleeding, frequent infections, bone or joint pain, and an enlarged spleen. Unusual blood test results, particularly a persistently high neutrophil count, are often the main trigger for ordering this test. If you have these symptoms along with abnormal white blood cell counts, this test can help clarify the underlying cause.

What is CSF3R and why does it matter?

CSF3R stands for colony stimulating factor 3 receptor, which is a protein on white blood cells that helps control how they grow and multiply. When this gene has certain mutations in exon 14 or exon 17, it can cause white blood cells to multiply abnormally, leading to rare conditions like atypical chronic myeloid leukemia or chronic neutrophilic leukemia. Identifying these mutations helps explain unusual blood cell patterns and supports more informed decisions about ongoing monitoring.

What does a positive result mean?

A positive result means a mutation was found in the CSF3R gene, which is associated with certain rare blood cancers affecting white blood cell production. This doesn't diagnose a specific condition on its own, but it's an important piece of information that, combined with your blood counts and symptoms, helps build a fuller picture. If your result is positive, seeking medical care promptly to discuss appropriate next steps is strongly recommended.

How often should I retest?

If you've never tested before and have concerning symptoms or blood counts, this is typically a one-time diagnostic test rather than something done on a regular schedule. If you've already tested positive and are monitoring a known condition, retesting frequency depends on how your condition is being managed, and your care team's monitoring plan will guide that timing. Talk through your specific retesting needs with your medical team based on your health history.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

CSF3R Mutation Analysis - Rare Leukemia Gene Test

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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