What's this test for?

This test is ideal if you're experiencing joint pain, skin rashes or discoloration, numbness, or circulation problems that seem to get worse in cold temperatures. It checks for abnormal proteins in your blood called cryoglobulins, which can be linked to autoimmune conditions, certain infections, or blood disorders. It's often used when unexplained symptoms point to a possible immune or blood-related cause.

What happens after I get my results?

Your results will show up in your account with a clear explanation of the normal range so you know exactly what your result means. If your result is positive, next steps usually involve additional testing to pinpoint the underlying cause, along with simple steps like keeping warm in cold weather and avoiding rapid temperature changes to reduce symptoms. Your standard lab report is downloadable anytime from your account, and you can track this result over time using the trends feature if you retest in the future. If your result suggests something urgent, such as severe circulation problems, seek medical care right away.

Who should consider this test?

This test is a good fit for people noticing joint aches, skin discoloration, or numbness that flares up in cold weather. It's also useful if you have a known autoimmune condition, liver disease, or certain infections and want to check for related complications. Anyone with unexplained circulation issues in fingers or toes may also benefit from checking this.

What symptoms indicate I may need this test?

Common symptoms include joint pain, purple or red skin patches, numbness or tingling in fingers and toes, and fatigue that worsens in cold weather. Some people also notice skin ulcers or bruising-like marks on their legs. If these symptoms come and go with temperature changes, it's worth checking your cryoglobulin levels.

When will I get my results?

Results are typically ready within about 7 days after your sample is collected. You'll get a notification as soon as your report is available in your account. Because this test requires special handling to keep your sample warm during transport, results can occasionally take a little longer than standard blood tests.

What is cryoglobulinemia and why does it matter?

Cryoglobulinemia is a condition where abnormal proteins clump together when your blood gets cold, which can block small blood vessels and cause inflammation. It matters because untreated cases can lead to lasting skin, nerve, kidney, or joint damage. Catching it early through testing lets you take steps sooner to manage the underlying cause.

What does a positive cryoglobulin result mean?

A positive result means abnormal proteins were found in your blood sample, which can be a sign of an autoimmune disease, chronic infection like hepatitis C, or certain blood cancers. It doesn't tell you the exact cause on its own, so follow-up testing is usually the next step. In the meantime, staying warm and avoiding cold exposure can help ease symptoms.

What causes abnormal cryoglobulin levels?

Abnormal levels are often linked to autoimmune diseases like lupus or rheumatoid arthritis, chronic infections such as hepatitis C, or blood and bone marrow disorders. In some cases, no clear cause is found, which is called essential cryoglobulinemia. Identifying the trigger usually requires looking at your full health picture, not just this one test.

How often should I retest?

If your first result is negative and you're symptom-free, you likely don't need to retest unless new symptoms appear. If you've been diagnosed with an underlying condition or had a positive result, retesting every few months can help you and your care routine track whether levels are changing. Using the trends feature makes it easy to see patterns over time.

What should I do if my results are abnormal?

Start by avoiding cold exposure as much as possible, since it can trigger or worsen symptoms. Keep a record of any new symptoms like joint pain, rashes, or numbness so you can share the pattern when seeking further evaluation. Follow-up testing is often recommended to identify the root cause, and your lab report will explain what additional steps make sense based on your specific result.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Cryoglobulin Test - Autoimmune & Circulation Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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